Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.35 |
| ▸ | CTSD | P07339 | 4/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.33 |
| ▸ | TACR2 | P21452 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5008495 | 0.78 | CTSD (0.40) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL2872653 | 0.78 | CTSD (0.40) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL3269625 | 0.78 | CTSD (0.40) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL18872524 | 0.71 | CTSD (0.42) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL5245588 | 0.70 | PIK3CD (0.44) | PIK3CD | |
| SCHEMBL23754416 | 0.66 | CTSD (0.40) | CTSD | |
| SCHEMBL31509493 | 0.66 | CTSD (0.40) | CTSD | |
| SCHEMBL13250134 | 0.66 | CTSD (0.40) | CTSD | |
| SCHEMBL9182647 | 0.65 | KEAP1 (0.41) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL5247488 | 0.64 | CTSD (0.30) | CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2065038-A1 | New therapeutic approaches for treating Charcot-Marie-Tooth disease | Pharnext (FR) | 2009-06-03 | — | — | EP | claimed |
| US-20140343104-A1 | OSTEOGENESIS PROMOTER AND USE THEREOF | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2014-11-20 | — | — | US | disclosed |
| EP-2749285-A1 | OSTEOGENESIS PROMOTER AND USE THEREOF | National University Corporation Nagoya University (JP) | 2014-07-02 | — | — | EP | disclosed |
| EP-2065038-A1 | New therapeutic approaches for treating Charcot-Marie-Tooth disease | Pharnext (FR) | 2009-06-03 | — | — | EP | disclosed |