Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 11/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2872653 | 1.00 | CTSD (0.40) | CTSDHDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL5008495 | 1.00 | CTSD (0.40) | CTSDHDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL9182647 | 0.83 | KEAP1 (0.41) | CTSDHDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL18872524 | 0.81 | CTSD (0.42) | CTSDHDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL23754416 | 0.80 | CTSD (0.40) | CTSD | |
| SCHEMBL31509493 | 0.80 | CTSD (0.40) | CTSD | |
| SCHEMBL13250134 | 0.80 | CTSD (0.40) | CTSD | |
| SCHEMBL18056086 | 0.79 | CTSD (0.33) | CTSD | |
| SCHEMBL8135687 | 0.78 | KEAP1 (0.31) | — | |
| SCHEMBL4457510 | 0.78 | PIK3CD (0.37) | CTSDHDAC1HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10092786-B2 | Fire extinguishing composition comprising aldoketones compound | XI'AN WESTPEACE FIRE TECHNOLOGY CO., LTD. (CN) | 2018-10-09 | — | — | US | claimed |
| EP-2594134-B1 | USE OF AN AGRICULTURAL AGENT CONTAINING 2,5-DIKETOPIPERAZINE DERIVATIVE AS ACTIVE INGREDIENT | REPUBLIC OF KOREA (MANAGEMENT: RURAL DEV ADMINISTRATION) (KR) | 2017-08-02 | — | — | EP | claimed |
| US-20160332016-A1 | Fire Extinguishing Composition Comprising Aldoketones Compound | NANO FIRE, LLC | 2016-11-17 | — | — | US | claimed |
| CN-103118540-B | Pesticide containing 2, 5-diketopiperazine derivative as active ingredient | Rural Development Office (KR) | 2016-02-17 | — | — | CN | claimed |
| US-20130190177-A1 | AGRICULTURAL AGENT CONTAINING 2,5-DIKETOPIPERAZINE DERIVATIVE AS ACTIVE INGREDIENT | Kongju National University Industry- University Cooperation Foundation (KR) | 2013-07-25 | — | — | US | claimed |
| EP-2594134-A2 | AGRICULTURAL CHEMICAL CONTAINING 2,5-DIKETOPIPERAZINE DERIVATIVE AS ACTIVE INGREDIENT | Republic of Korea (Management: Rural Development Administration) (KR) | 2013-05-22 | — | — | EP | claimed |
| CN-116925924-A | England thistle endophytic fungi Bartalinia pondoensis wz03 and application thereof | 华侨大学 | 2023-10-24 | — | — | CN | disclosed |
| CN-116925924-A | England thistle endophytic fungi Bartalinia pondoensis wz03 and application thereof | 华侨大学 | 2023-10-24 | — | — | CN | disclosed |
| US-10745400-B2 | Inhibition of BMP signaling, compounds, compositions and uses thereof | VANDERBUILT UNIVERSITY (US) | 2020-08-18 | — | — | US | disclosed |
| US-20190284183-A1 | INHIBITION OF BMP SIGNALING, COMPOUNDS, COMPOSITIONS AND USES THEREOF | LA JOLLA PHARMACEUTICAL COMPANY | 2019-09-19 | — | — | US | disclosed |
| US-10092786-B2 | Fire extinguishing composition comprising aldoketones compound | XI'AN WESTPEACE FIRE TECHNOLOGY CO., LTD. (CN) | 2018-10-09 | — | — | US | disclosed |
| EP-2594134-B1 | USE OF AN AGRICULTURAL AGENT CONTAINING 2,5-DIKETOPIPERAZINE DERIVATIVE AS ACTIVE INGREDIENT | REPUBLIC OF KOREA (MANAGEMENT: RURAL DEV ADMINISTRATION) (KR) | 2017-08-02 | — | — | EP | disclosed |
| US-20170210749-A1 | THERAPEUTICALLY ACTIVE COMPOSITIONS AND THEIR METHODS OF USE | SERVIER PHARMACEUTICALS LLC | 2017-07-27 | — | — | US | disclosed |
| US-20030232837-A1 | 17-Beta hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases | SCHERING CORPORATION | 2003-12-18 | — | — | US | disclosed |
| WO-2003033487-A1 | PIPERIDINE- AND PIPERAZINEACETAMINES AS 17BETA HYDROXYSTEROID DEHYDROGENASE TYPE 3 INHIBITORS FOR THE TREATMENT OF ANDROGEN DEPENDENT DISEASES | SCHERING CORPORATION (US) | 2003-04-24 | — | — | WO | disclosed |
| WO-2003022835-A1 | 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 3 INHIBITORS FOR THE TREATMENT OF ANDROGEN DEPENDENT DISEASES | SCHERING CORPORATION (US) | 2003-03-20 | — | — | WO | disclosed |
| US-20030008882-A1 | Proteomimetic compounds and methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-01-09 | — | — | US | disclosed |
| WO-2002089738-A2 | PROTEOMIMETIC COMPOUNDS AND METHODS | YALE UNIVERSITY (US) | 2002-11-14 | — | — | WO | disclosed |
| EP-1228066-A2 | SULFONAMIDE DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001032646-A2 | SULFONAMIDE DERIVATIVES | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030008882-A1 | Proteomimetic compounds and methods | PACSIN2, HSP90B1, PHLPP2 | CTSD 2519/4885HDAC1 3491/4885HDAC3 3842/4885 |
| US-20030232837-A1 | 17-Beta hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases | HSD17B3, HSD17B1, HSD17B11 | CTSD 2112/4885HDAC1 444/4885HDAC3 817/4885 |
| US-20130190177-A1 | AGRICULTURAL AGENT CONTAINING 2,5-DIKETOPIPERAZINE DERIVATIVE AS ACTIVE INGREDIENT | HDHD5, DAZAP1, MAPKAPK5 | CTSD 2473/4885HDAC1 130/4885HDAC3 431/4885 |
| US-20170210749-A1 | THERAPEUTICALLY ACTIVE COMPOSITIONS AND THEIR METHODS OF USE | RNASE1, GZMB, ANXA2 | CTSD 1119/4885HDAC1 143/4885HDAC3 148/4885 |
| US-20190284183-A1 | INHIBITION OF BMP SIGNALING, COMPOUNDS, COMPOSITIONS AND USES THEREOF | BMP1, BMP4, BMP2 | CTSD 3480/4885HDAC1 1291/4885HDAC3 1131/4885 |
| US-10745400-B2 | Inhibition of BMP signaling, compounds, compositions and uses thereof | BMP1, BMP4, BMP2 | CTSD 3480/4885HDAC1 1291/4885HDAC3 1131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.