Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 12/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5405317 | 0.81 | SLC6A4 (0.59) | SLC6A4DRD2SLC6A3SLC6A2CYP2D6 | |
| SCHEMBL4458583 | 0.80 | SLC6A4 (0.55) | SLC6A4DRD2SLC6A3SLC6A2CYP2D6 | |
| Methyl Alcohol SCHEMBL10694365 | 0.80 | SLC6A4 (0.58) | SLC6A4DRD2SLC6A3SLC6A2CYP2D6 | |
| SCHEMBL7128350 | 0.77 | AKR1C3 (0.50) | DRD2 | |
| SCHEMBL5756712 | 0.77 | SLC6A4 (0.46) | SLC6A4DRD2SLC6A3SLC6A2CYP2D6 | |
| SCHEMBL5757587 | 0.77 | SLC6A4 (0.46) | SLC6A4DRD2SLC6A3SLC6A2CYP2D6 | |
| SCHEMBL736266 | 0.77 | SLC6A4 (0.50) | SLC6A4DRD2SLC6A3SLC6A2CYP2D6 | |
| SCHEMBL5090671 | 0.77 | SLC6A4 (0.46) | SLC6A4DRD2SLC6A3SLC6A2CYP2D6 | |
| SCHEMBL5757581 | 0.77 | SLC6A4 (0.46) | SLC6A4DRD2SLC6A3SLC6A2CYP2D6 | |
| SCHEMBL7123942 | 0.77 | SLC6A4 (0.46) | SLC6A4DRD2SLC6A3SLC6A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009145357-A1 | IN 1-POSITION DURCH EINEN RING SUBSTITUIERTE BENZO [1, 4] DIAZEPINE ZUR VERWENDUNGS ALS ANTIDEPRESSIVA | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2009-12-03 | — | — | WO | disclosed |