Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 13/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.50 |
| ▸ | KDM1A | O60341 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8226408 | 0.79 | KDM1A (0.54) | KDM1AMAOB | |
| SCHEMBL5405317 | 0.78 | SLC6A4 (0.59) | SLC6A4SLC6A3SLC6A2KDM1AMAOB | |
| Methyl Alcohol SCHEMBL10694365 | 0.77 | SLC6A4 (0.58) | SLC6A4SLC6A3SLC6A2DRD2CYP2D6 | |
| SCHEMBL4457596 | 0.77 | SLC6A4 (0.48) | SLC6A4SLC6A3SLC6A2KDM1AMAOB | |
| SCHEMBL25965319 | 0.76 | KDM1A (0.75) | SLC6A4SLC6A2KDM1AMAOBMAOA | |
| SCHEMBL735622 | 0.75 | SLC6A2 (0.50) | SLC6A4SLC6A3SLC6A2DRD2CYP2D6 | |
| SCHEMBL734050 | 0.74 | LMNA (0.38) | SLC6A4KDM1AMAOBCYP2D6HTR2C | |
| SCHEMBL4458583 | 0.74 | SLC6A4 (0.55) | SLC6A4SLC6A3SLC6A2DRD2CYP2D6 | |
| SCHEMBL23873831 | 0.72 | KDM1A (0.42) | KDM1AMAOBKCNH2HTR2C | |
| Hydrochloric Acid SCHEMBL4134459 | 0.71 | SLC6A4 (0.59) | SLC6A4SLC6A3SLC6A2KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138377-B2 | Arylbicyclo[3.1.0]hexylamines and methods and compositions for their preparation and use | DOV PHARMACEUTICAL, INC. (US) | 2012-03-20 | — | — | US | disclosed |
| US-20080293822-A1 | Novel Arylbicyclo[3.1.0]Hexylamines And Methods And Compositions For Their Preparation And Use | ETHISMOS RESEARCH, INC. | 2008-11-27 | — | — | US | disclosed |
| US-20080269348-A1 | Novel Arylbicyclo[3.1.0]Hexylamines And Methods And Compositions For Their Preparation And Use | ETHISMOS RESEARCH, INC. | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293822-A1 | Novel Arylbicyclo[3.1.0]Hexylamines And Methods And Compositions For Their Preparation And Use | HTR2C, HTR1B, HTR3C | SLC6A4 93/4885SLC6A3 76/4885SLC6A2 150/4885 |
| US-20080269348-A1 | Novel Arylbicyclo[3.1.0]Hexylamines And Methods And Compositions For Their Preparation And Use | HTR2C, HTR1B, HTR3C | SLC6A4 93/4885SLC6A3 76/4885SLC6A2 150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.