Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.72 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.72 |
| ▸ | MMP14 | P50281 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.57 |
| ▸ | MEN1 | O00255 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | IDO1 | P14902 | 3/20 | 0.57 |
| ▸ | TDO2 | P48775 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | CASP6 | P55212 | 1/20 | 0.57 |
| ▸ | MPI | P34949 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16207365 | 0.84 | KDM4E (0.62) | HSP90AA1HSP90AB1MMP14KDM4EMEN1 | |
| SCHEMBL113119 | 0.79 | KDM4E (0.72) | HSP90AA1HSP90AB1MMP14KDM4EMEN1 | |
| SCHEMBL30153812 | 0.79 | KDM4E (0.72) | HSP90AA1HSP90AB1MMP14KDM4EMEN1 | |
| SCHEMBL115570 | 0.79 | KDM4E (0.72) | HSP90AA1MMP14KDM4EMEN1KMT2A | |
| SCHEMBL4467681 | 0.79 | KDM4E (0.72) | HSP90AA1HSP90AB1MMP14KDM4EMEN1 | |
| SCHEMBL113528 | 0.79 | KDM4E (0.72) | HSP90AA1HSP90AB1MMP14KDM4EMEN1 | |
| SCHEMBL12292143 | 0.79 | HSP90AA1 (0.72) | HSP90AA1HSP90AB1MMP14KDM4EMEN1 | |
| SCHEMBL7743581 | 0.79 | L3MBTL1 (0.50) | HSP90AA1HSP90AB1MMP14KDM4EMEN1 | |
| SCHEMBL22446563 | 0.79 | L3MBTL1 (0.57) | HSP90AA1HSP90AB1MMP14KDM4EMEN1 | |
| SCHEMBL2110200 | 0.79 | MMP14 (1.00) | HSP90AA1HSP90AB1MMP14KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140215-A2 | METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS | GERAGHTY, ERIN (US) | 2009-11-19 | — | — | WO | claimed |
| WO-2009140215-A2 | METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS | GERAGHTY, ERIN (US) | 2009-11-19 | — | — | WO | disclosed |