Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.65 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | FAAH2 | Q6GMR7 | 1/20 | 0.59 |
| ▸ | MGLL | Q99685 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31418197 | 0.91 | FAAH (0.60) | FAAHTRPA1EPHX2FAAH2MGLL | |
| SCHEMBL31418231 | 0.91 | FAAH (0.60) | FAAHTRPA1EPHX2FAAH2MGLL | |
| SCHEMBL31418259 | 0.90 | FAAH (0.58) | FAAHTRPA1EPHX2FAAH2MGLL | |
| SCHEMBL30039761 | 0.81 | RAB9A (0.54) | — | |
| SCHEMBL29393643 | 0.80 | FAAH (1.00) | FAAHTRPA1EPHX2FAAH2MGLL | |
| SCHEMBL530169 | 0.80 | FAAH (1.00) | FAAHTRPA1EPHX2FAAH2MGLL | |
| SCHEMBL10089418 | 0.78 | FAAH (0.97) | FAAHTRPA1EPHX2FAAH2MGLL | |
| SCHEMBL4750632 | 0.78 | FAAH (0.65) | FAAHTRPA1EPHX2FAAH2MGLL | |
| SCHEMBL31417872 | 0.77 | FAAH (0.44) | FAAH | |
| SCHEMBL31418246 | 0.77 | FAAH (0.44) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008129129-A1 | HETEROCYCLIC PHENYL CARBAMATES AS NOVEL FAAH-INHIBITORS | KUOPION YLIOPISTO (FI) | 2008-10-30 | — | — | WO | claimed |
| WO-2008129129-A1 | HETEROCYCLIC PHENYL CARBAMATES AS NOVEL FAAH-INHIBITORS | KUOPION YLIOPISTO (FI) | 2008-10-30 | — | — | WO | disclosed |