Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13434089 | 0.79 | KMT2A (0.77) | MEN1KMT2AL3MBTL1LMNAALDH1A1 | |
| SCHEMBL19349131 | 0.79 | MEN1 (0.61) | MEN1KMT2AL3MBTL1LMNAALDH1A1 | |
| SCHEMBL8483211 | 0.77 | LTB4R2 (0.53) | AGTR1LTB4R2 | |
| SCHEMBL3463258 | 0.77 | ALDH1A1 (0.60) | AGTR1MEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL10911381 | 0.76 | L3MBTL1 (0.76) | MEN1KMT2AL3MBTL1LMNAALDH1A1 | |
| SCHEMBL10911385 | 0.76 | L3MBTL1 (0.76) | MEN1KMT2AL3MBTL1LMNAALDH1A1 | |
| SCHEMBL11164223 | 0.76 | KMT2A (0.57) | MEN1KMT2AL3MBTL1LMNAALDH1A1 | |
| SCHEMBL3463311 | 0.75 | MEN1 (0.53) | MEN1KMT2AL3MBTL1LMNAALDH1A1 | |
| SCHEMBL3462963 | 0.75 | LMNA (0.57) | MEN1KMT2AL3MBTL1LMNAALDH1A1 | |
| SCHEMBL1883194 | 0.74 | MEN1 (0.56) | MEN1KMT2AL3MBTL1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2084519-A2 | ADVANCED DRUG DEVELOPMENT AND MANUFACTURING | Los Alamos National Security, LLC (US) | 2009-08-05 | — | — | EP | disclosed |
| WO-2008127291-A2 | ADVANCED DRUG DEVELOPMENT AND MANUFACTURING | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2008-10-23 | — | — | WO | disclosed |