Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 10/20 | 0.56 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2109899 | 0.77 | HSP90AA1 (0.56) | ADAMTS5KMT2AKDM4ETDP1MEN1 | |
| SCHEMBL14775771 | 0.76 | L3MBTL1 (0.59) | KMT2AKDM4ETDP1MEN1LMNA | |
| SCHEMBL13236176 | 0.73 | KMT2A (0.77) | ADAMTS5ADAMTS4KMT2AKDM4ETDP1 | |
| SCHEMBL8344356 | 0.73 | KDM4E (0.62) | ADAMTS5ADAMTS4KMT2AKDM4ETDP1 | |
| SCHEMBL15783247 | 0.72 | ADAMTS5 (0.70) | ADAMTS5ADAMTS4KMT2AKDM4ETDP1 | |
| SCHEMBL1814553 | 0.72 | ADAMTS5 (1.00) | ADAMTS5ADAMTS4 | |
| SCHEMBL2111796 | 0.71 | NPC1 (0.54) | ADAMTS5KMT2AKDM4ETDP1MEN1 | |
| SCHEMBL1814563 | 0.71 | ADAMTS5 (1.00) | ADAMTS5ADAMTS4KDM4EHSP90AA1ALOX12 | |
| SCHEMBL2153797 | 0.71 | TP53 (0.74) | ADAMTS5ADAMTS4KMT2ATDP1MEN1 | |
| SCHEMBL1816125 | 0.71 | ADAMTS5 (0.86) | ADAMTS5ADAMTS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140215-A2 | METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS | GERAGHTY, ERIN (US) | 2009-11-19 | — | — | WO | claimed |
| WO-2009140215-A2 | METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS | GERAGHTY, ERIN (US) | 2009-11-19 | — | — | WO | disclosed |