Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 6/20 | 0.64 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.43 |
| ▸ | RHEB | Q15382 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CRHBP | P24387 | 2/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26428597 | 0.84 | AHR (0.46) | AHRCYP1B1ESR2ALDH1A1AKR1C2 | |
| SCHEMBL29419465 | 0.84 | AHR (0.46) | AHRCYP1B1ESR2ALDH1A1AKR1C2 | |
| SCHEMBL25489732 | 0.84 | CRHBP (0.54) | AHRCYP1B1ESR2ALDH1A1AKR1C2 | |
| SCHEMBL22939763 | 0.83 | AHR (0.64) | AHRCYP1B1ESR2ALDH1A1AKR1C2 | |
| SCHEMBL2906064 | 0.82 | AHR (0.67) | AHRCYP1B1ALDH1A1HSP90AA1HPGD | |
| SCHEMBL16939188 | 0.81 | ESR2 (0.52) | AHRESR2ALDH1A1AKR1C2AKR1C1 | |
| SCHEMBL16934967 | 0.81 | ESR2 (0.52) | AHRCYP1B1ESR2ALDH1A1AKR1C2 | |
| Biphenyl SCHEMBL10490134 | 0.80 | CYP2A6 (0.55) | AHRESR2ALDH1A1CYP1A2MEN1 | |
| SCHEMBL3827276 | 0.79 | ESR2 (0.50) | AHRESR2ALDH1A1AKR1C2AKR1C1 | |
| SCHEMBL22141287 | 0.79 | ESR2 (0.50) | AHRESR2ALDH1A1AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220131086-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2022-04-28 | — | — | US | disclosed |
| US-20210126195-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2021-04-29 | — | — | US | disclosed |
| US-8653119-B2 | Methods for treating transthyretin amyloid diseases | THE SCRIPPS RESEARCH INSTITUTE (US) | 2014-02-18 | — | — | US | disclosed |
| US-8168663-B2 | Pharmaceutically acceptable salt of 6-carboxy-2-(3,5 dichlorophenyl)-benzoxazole, and a pharmaceutical composition comprising the salt thereof | THE SCRIPPS RESEARCH INSTITUTE (US) | 2012-05-01 | — | — | US | disclosed |
| US-20100120919-A1 | METHODS FOR TREATING TRANSTHYRETIN AMYLOID DISEASES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-05-13 | — | — | US | disclosed |
| US-20090269857-A1 | Instruments for detecting low-molecular weight substance | FUJIKURA KASEI CO., LTD. (JP) | 2009-10-29 | — | — | US | disclosed |
| US-20050148097-A1 | Instruments for detecting low-molecular weight substance | ENBIOTEC LABORATORIES C., LTD. (JP) | 2005-07-07 | — | — | US | disclosed |
| EP-1489420-A1 | INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE | Enbiotec Laboratories Co., Ltd. (JP) | 2004-12-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210126195-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE | SLC25A21, SLCO4C1, TMEM109 | AHR 2067/4885CYP1B1 838/4885ESR2 170/4885 |
| US-20100120919-A1 | METHODS FOR TREATING TRANSTHYRETIN AMYLOID DISEASES | TTR, TTPA, PRNP | AHR 4301/4885CYP1B1 4049/4885ESR2 4175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.