Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4458415 | 1.00 | ELOVL1 (0.46) | ELOVL1MAPTGAAMEN1KMT2A | |
| SCHEMBL4468259 | 0.82 | ELOVL1 (0.47) | ELOVL1MAPTGAAMEN1KMT2A | |
| SCHEMBL4457435 | 0.80 | CSNK1D (0.46) | MAPTGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL4457438 | 0.80 | CSNK1D (0.46) | MAPTGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL4455136 | 0.80 | HDAC3 (0.56) | ELOVL1MAPTGAAMEN1KMT2A | |
| SCHEMBL4455141 | 0.80 | HDAC3 (0.56) | ELOVL1MAPTGAAMEN1KMT2A | |
| SCHEMBL4456589 | 0.80 | MEN1 (0.43) | GAAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL4456592 | 0.80 | MEN1 (0.43) | GAAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL4465417 | 0.78 | ALDH1A1 (0.47) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL4465412 | 0.78 | ALDH1A1 (0.47) | MAPTMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |