Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4458423 | 0.82 | ELOVL1 (0.46) | ELOVL1MAPTADORA3MEN1KMT2A | |
| SCHEMBL4458415 | 0.82 | ELOVL1 (0.46) | ELOVL1MAPTADORA3MEN1KMT2A | |
| SCHEMBL4455136 | 0.82 | HDAC3 (0.56) | ELOVL1MAPTADORA3MEN1KMT2A | |
| SCHEMBL4455141 | 0.82 | HDAC3 (0.56) | ELOVL1MAPTADORA3MEN1KMT2A | |
| SCHEMBL4459664 | 0.79 | CSNK1D (0.48) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL4459671 | 0.79 | CSNK1D (0.48) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL12678090 | 0.78 | ELOVL1 (0.60) | ELOVL1MAPTADORA3MEN1KMT2A | |
| SCHEMBL9179947 | 0.78 | ELOVL1 (0.60) | ELOVL1MAPTADORA3MEN1KMT2A | |
| SCHEMBL4455498 | 0.77 | ALDH1A1 (0.49) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL19134400 | 0.75 | ROCK2 (0.56) | ELOVL1MAPTADORA3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | claimed |
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |