Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | PPID | Q08752 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5842032 | 0.91 | SMN1; SMN2 (0.49) | SMN1; SMN2MEN1KMT2ACTDSP1TSHR | |
| SCHEMBL27599056 | 0.91 | SMN1; SMN2 (0.49) | SMN1; SMN2MEN1KMT2ACTDSP1GAA | |
| SCHEMBL4460270 | 0.86 | LMNA (0.51) | SMN1; SMN2TSHRGAAALDH1A1GLA | |
| SCHEMBL28751721 | 0.85 | ALDH1A1 (0.54) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8624227 | 0.85 | SMN1; SMN2 (0.57) | SMN1; SMN2MEN1KMT2ACTDSP1TSHR | |
| SCHEMBL3662111 | 0.84 | SMN1; SMN2 (0.55) | SMN1; SMN2MEN1KMT2ACTDSP1TSHR | |
| SCHEMBL557889 | 0.84 | SMN1; SMN2 (0.55) | SMN1; SMN2MEN1KMT2ACTDSP1TSHR | |
| SCHEMBL6608700 | 0.83 | SMN1; SMN2 (0.46) | SMN1; SMN2MEN1KMT2ACTDSP1TSHR | |
| SCHEMBL4459514 | 0.83 | TSHR (0.51) | SMN1; SMN2MEN1KMT2ATSHRGAA | |
| SCHEMBL8089314 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2MEN1KMT2ACTDSP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053658-A | A kind of new method preparing Ao Gelieting key intermediate | 长沙理工大学 | 2018-12-21 | — | — | CN | disclosed |
| CN-106946886-A | The new crystalline form of inhibitors of dipeptidyl IV | 默沙东公司 | 2017-07-14 | — | — | CN | disclosed |
| US-9181262-B2 | Crystalline forms of a dipeptidyl peptidase-IV inhibitors | MERCK SHARP & DOHME CORP (US) | 2015-11-10 | — | — | US | disclosed |
| US-20150099891-A1 | NOVEL CRYSTALLINE FORMS OF A DIPEPTIDYL PEPTIDASE-IV INHIBITORS | MERCK SHARP & DOHME LLC | 2015-04-09 | — | — | US | disclosed |
| US-8895603-B2 | Crystalline forms of a dipeptidyl peptidase-IV inhibitor | MERCK SHARP & DOHME CORP. (US) | 2014-11-25 | — | — | US | disclosed |
| CN-103987388-A | Novel crystalline forms of dipeptidyl peptidase-IV inhibitors | MERCK SHARP & DOHME | 2014-08-13 | — | — | CN | disclosed |
| EP-2726075-A1 | NOVEL CRYSTALLINE FORMS OF A DIPEPTIDYL PEPTIDASE-IV INHIBITOR | Merck Sharp & Dohme Corp. (US) | 2014-05-07 | — | — | EP | disclosed |
| US-20140080884-A1 | NOVEL CRYSTALLINE FORMS OF A DIPEPTIDYL PEPTIDASE-IV INHIBITOR | MERCK SHARP & DOHME LTD. (GB) | 2014-03-20 | — | — | US | disclosed |
| WO-2013003249-A1 | NOVEL CRYSTALLINE FORMS OF A DIPEPTIDYL PEPTIDASE-IV INHIBITOR | MERCK SHARP & DOHME CORP. (US) | 2013-01-03 | — | — | WO | disclosed |
| US-20090189127-A1 | Optical resin lens and production method for optical resin material | KONICA MINOLTA OTPO, INC. (JP) | 2009-07-30 | — | — | US | disclosed |
| CN-1910477-A | Optical resin lens and method for producing optical resin material | KONICA MINOLTA OPTO INC (JP) | 2007-02-07 | — | — | CN | disclosed |
| EP-1717607-A1 | OPTICAL RESIN LENS AND METHOD FOR PRODUCING OPTICAL RESIN MATERIAL | Konica Minolta Opto, Inc. (JP) | 2006-11-02 | — | — | EP | disclosed |
| US-4507450-A | COORDINATION CATALYSTS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1985-03-26 | — | — | US | disclosed |
| US-4229558-A | HAVING HIGH ISOTACTIC INDEX BY USING A CATALYST PREPARED FROM A MAGNESIUM GRIGNARD REAGENT, TITANIUM HALIDE AN ETHER AND A CARBOXYLIC ESTER COMBINED WITH AN ORGANOALUMINUM COMPOUND | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1980-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150099891-A1 | NOVEL CRYSTALLINE FORMS OF A DIPEPTIDYL PEPTIDASE-IV INHIBITORS | DPP4, DPP3, DPP7 | SMN1; SMN2 4219/4885MEN1 3757/4885KMT2A 1907/4885 |
| US-20140080884-A1 | NOVEL CRYSTALLINE FORMS OF A DIPEPTIDYL PEPTIDASE-IV INHIBITOR | DPP4, DPP3, DPP7 | SMN1; SMN2 4253/4885MEN1 3718/4885KMT2A 1960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.