Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL291237 | 0.85 | TSHR (0.61) | ALDH1A1TSHRCA2CA1CA12 | |
| SCHEMBL13934004 | 0.76 | ALDH1A1 (0.67) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL7398501 | 0.74 | TSHR (0.54) | ALDH1A1TSHRCA2CA1CA12 | |
| SCHEMBL8094543 | 0.74 | POLB (0.68) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL4686740 | 0.73 | CA1 (0.55) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL17737220 | 0.73 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL4686733 | 0.73 | CA1 (0.55) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL11581058 | 0.73 | CHKA (0.55) | — | |
| SCHEMBL28531315 | 0.72 | TSHR (0.60) | ALDH1A1TSHRCA2CA1CA12 | |
| SCHEMBL44366 | 0.72 | POLB (0.76) | ALDH1A1MEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103168899-A | Menthyl ester containing cooling compositions | KRAFT FOODS GLOBAL BRANDS LLC | 2013-06-26 | — | — | CN | disclosed |
| CN-101282707-B | Cooling compositions comprising menthyl esters | KRAFT FOODS GLOBAL BRANDS LLC | 2013-03-27 | — | — | CN | disclosed |
| EP-2559424-A1 | Cooling composition comprising trimethyl isopropyl butanamide | Kraft Foods Global Brands LLC (US) | 2013-02-20 | — | — | EP | disclosed |
| CN-100466915-C | Menthyl half acid ester dirivatives, processes for preparing same, and uses thereof for their cooling/refreshing effect in consumable materials | INT FLAVORS & FRAGRANCES INC (US) | 2009-03-11 | — | — | CN | disclosed |
| EP-1493336-B1 | Monomenthyl ester derivatives of dicarboxylic acids, processes for preparing same, and uses thereof for their cooling/refreshing effect in consumable materials | INT FLAVORS & FRAGRANCES INC (US) | 2009-02-25 | — | — | EP | disclosed |
| CN-101282707-A | Cooling compositions comprising menthyl esters | CADBURY ADAMS USA LLC (US) | 2008-10-08 | — | — | CN | disclosed |
| US-20070221236-A1 | Cooling compositions including menthyl esters | CADBURY ADAMS USA LLC. | 2007-09-27 | — | — | US | disclosed |
| US-20070077331-A1 | Cooling compositions | CADBURY ADAMS USA LLC. | 2007-04-05 | — | — | US | disclosed |
| US-6884906-B2 | Menthyl half acid ester derivatives, processes for preparing same, and uses thereof for their cooling/refreshing effect in consumable materials | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2005-04-26 | — | — | US | disclosed |
| CN-1575660-A | Menthyl half acid ester dirivatives, processes for preparing same, and uses thereof for their cooling/refreshing effect in consumable materials | INT FLAVORS & FRAGRANCES INC (US) | 2005-02-09 | — | — | CN | disclosed |
| US-20050004214-A1 | MENTHYL HALF ACID ESTER DIRIVATIVES, PROCESSES FOR PREPARING SAME, AND USES THEREOF FOR THEIR COOLING/REFRESHING EFFECT IN CONSUMABLE MATERIALS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2005-01-06 | — | — | US | disclosed |
| EP-1493336-A2 | Monomenthyl ester derivatives of dicarboxylic acids, processes for preparing same, and uses thereof for their cooling/refreshing effect in consumable materials | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2005-01-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004214-A1 | MENTHYL HALF ACID ESTER DIRIVATIVES, PROCESSES FOR PREPARING SAME, AND USES THEREOF FOR THEIR COOLING/REFRESHING EFFECT IN CONSUMABLE MATERIALS | TAS2R41, TAS2R1, TAS1R3 | ALDH1A1 1172/4885MEN1 112/4885KMT2A 2140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.