Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17823015 | 0.70 | HDAC8 (0.37) | — | |
| Cyclohexane Carboxamide SCHEMBL28306040 | 0.66 | CES2 (0.52) | — | |
| SCHEMBL28636550 | 0.66 | CES2 (0.58) | — | |
| SCHEMBL30542351 | 0.66 | CES2 (0.58) | — | |
| SCHEMBL30542352 | 0.66 | CES2 (0.58) | — | |
| SCHEMBL25485911 | 0.66 | CES2 (0.58) | — | |
| SCHEMBL217106 | 0.66 | CES2 (0.58) | — | |
| Cyclohexane Carboxamide SCHEMBL26181 | 0.66 | — | — | |
| SCHEMBL218387 | 0.66 | CES2 (0.58) | — | |
| SCHEMBL217428 | 0.66 | CES2 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3950734-A1 | PRODUCTION METHOD FOR CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, PRODUCTION METHOD FOR CATALYST FOR OLEFIN POLYMERIZATION, AND PRODUCTION METHOD FOR OLEFIN POLYMER | Japan Polypropylene Corporation (JP) | 2022-02-09 | — | — | EP | disclosed |
| US-20090069171-A1 | Catalysts for olefin polymerization, process for production of the catalysts, and method for preservation thereof | JAPAN POLYPROPYLENE CORPORATION (JP) | 2009-03-12 | — | — | US | disclosed |