SCHEMBL4458824

SCHEMBL4458824

OP(O)(=S)Oc1ccccn1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.41
LMNA P02545 3/20 0.41
CCR1 P32246 2/20 0.41
CCR5 P51681 2/20 0.41
CCR8 P51685 2/20 0.41
CYP1A2 P05177 1/20 0.41
POLB P06746 1/20 0.41
METAP1 P53582 1/20 0.41
BLM P54132 1/20 0.41
HIF1A Q16665 1/20 0.41
DOHH Q9BU89 1/20 0.41
P4HTM Q9NXG6 1/20 0.41
NOS3 P29474 1/20 0.38
NOS1 P29475 1/20 0.38
NOS2 P35228 1/20 0.38
PI4KA P42356 1/20 0.38
PI4K2B Q8TCG2 1/20 0.38
PI4K2A Q9BTU6 1/20 0.38
PI4KB Q9UBF8 1/20 0.38
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11631051 0.82 CA2 (0.39) KDM4ELMNACCR1CCR5CCR8
SCHEMBL9806698 0.79 KDM4E (0.46) KDM4ELMNACCR1CCR5CCR8
SCHEMBL3514513 0.79 SRC (0.48) KDM4ELMNACCR1CCR5CCR8
SCHEMBL28997266 0.78 SRC (0.47) KDM4ELMNACCR1CCR5CCR8
SCHEMBL27213564 0.76 TSHR (0.41) KDM4ELMNACCR1CCR5CCR8
SCHEMBL10662464 0.76 FDPS (0.40) KDM4ELMNACCR1CCR5CCR8
SCHEMBL11408610 0.75 TSHR (0.37) KDM4ELMNACCR1CCR5CCR8
SCHEMBL31734268 0.74 KDM4E (0.44) KDM4ELMNACCR1CCR5CCR8
SCHEMBL435144 0.74 KDM4E (0.44) KDM4ELMNACCR1CCR5CCR8
SCHEMBL6576573 0.74 KDM4E (0.44) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4462995-A ANIMAL GROWTH REGULATORS; ANIMAL HUSBANDRY THE DOW CHEMICAL COMPANY (US) 1984-07-31 US claimed
CN-102271516-A Stable insecticide compositions and methods for producing same 2011-12-07 CN disclosed
CN-101541750-A Insecticidal N-substituted (heteroaryl) cycloalkyl sulfoximines DOW AGROSCIENCES LLC (US) 2009-09-23 CN disclosed
CN-101541771-A Insecticidal N-substituted (2- sudstituted-1,3-thiazol) alkyl sulfoximines DOW AGROSCIENCES LLC (US) 2009-09-23 CN disclosed
CN-101534646-A Use of N-substituted sulfoximines for controlling invertebrate pests DOW AGROSCIENCES LLC (US) 2009-09-16 CN disclosed
CN-101535262-A Heteroaryl (substituted) alkyl n-substituted sulfoximines as insecticides DOW AGROSCIENCES LLC (US) 2009-09-16 CN disclosed
CN-101535261-A Insecticidal N-substituted (heteroaryl) alkyl sulfilimines DOW AGROSCIENCES LLC (US) 2009-09-16 CN disclosed
CN-101535263-A Polysubstituted pyridyl sulfoximines and their use as pesticides DOW AGROSCIENCES LLC (US) 2009-09-16 CN disclosed
EP-2084214-A1 TREATED EXPANDED POLYSTYRENE FOAM Lanxess Corporation (US) 2009-08-05 EP disclosed
WO-2008051392-A1 TREATED EXPANDED POLYSTYRENE FOAM LANXESS CORPORATION (US) 2008-05-02 WO disclosed
EP-0005827-B1 METHOD OF REMOVING CONTAMINANTS FROM WATER THE DOW CHEMICAL COMPANY (US) 1988-06-08 EP disclosed
US-4462995-A ANIMAL GROWTH REGULATORS; ANIMAL HUSBANDRY THE DOW CHEMICAL COMPANY (US) 1984-07-31 US disclosed
US-RE29238-E 2-CHLOROALLYL DIETHYLDITHIOCARBAMATE; HERBICIDE WESTVACO CORPORATION (US) 1977-05-31 US disclosed