SCHEMBL3514513

SCHEMBL3514513

O=P(O)(O)Oc1ccccn1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 2/20 0.48
FDPS P14324 4/20 0.42
KDM4E B2RXH2 3/20 0.41
LMNA P02545 1/20 0.41
CYP1A2 P05177 1/20 0.41
POLB P06746 1/20 0.41
CCR1 P32246 1/20 0.41
CCR5 P51681 1/20 0.41
CCR8 P51685 1/20 0.41
METAP1 P53582 1/20 0.41
BLM P54132 1/20 0.41
HIF1A Q16665 1/20 0.41
DOHH Q9BU89 1/20 0.41
P4HTM Q9NXG6 1/20 0.41
INPPL1 O15357 4/20 0.41
INPP5A Q14642 4/20 0.41
INPP5B P32019 2/20 0.41
USP2 O75604 1/20 0.40
ALDH1A1 P00352 1/20 0.40
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28997266 0.98 SRC (0.47) SRCFDPSKDM4ELMNACYP1A2
SCHEMBL9806698 0.88 KDM4E (0.46) SRCFDPSKDM4ELMNACYP1A2
SCHEMBL28901681 0.85 SRC (0.38) SRCFDPSKDM4ELMNACYP1A2
SCHEMBL10662464 0.84 FDPS (0.40) SRCFDPSKDM4ELMNACYP1A2
SCHEMBL27213564 0.84 TSHR (0.41) SRCFDPSKDM4ELMNACYP1A2
SCHEMBL6576573 0.83 KDM4E (0.44) KDM4ELMNACYP1A2POLBCCR1
SCHEMBL11063572 0.81 CA2 (0.47) SRCFDPSKDM4ELMNAP4HTM
SCHEMBL27701388 0.80 FDPS (0.42) SRCFDPSKDM4ELMNACYP1A2
SCHEMBL27447072 0.80 TSHR (0.44) FDPSKDM4ELMNACYP1A2ALDH1A1
SCHEMBL4458824 0.79 KDM4E (0.41) FDPSKDM4ELMNACYP1A2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4888174-A Insecticidal polymeric compositions THE DOW CHEMICAL COMPANY (US) 1989-12-19 US claimed
US-4810793-A THERMOPLASTIC RESINS THE DOW CHEMICAL COMPANY (US) 1989-03-07 US claimed
US-4631301-A STABILIZING ON O-PYRIDYL PHOSPHATE INSECTICIDE WITH PHTHALATE ESTERS; FOR CABLES AND PIPELINES DOW CHEMICAL JAPAN LIMITED (JP) 1986-12-23 US claimed
US-4083971-A PESTICIDES BASF AKTIENGESELLSCHAFT (DT) 1978-04-11 US claimed
CN-116768859-A Azolopyrimidines for the treatment of cancer related disorders 艾库斯生物科学有限公司 2023-09-19 CN disclosed
CN-116365023-A Lithium ion battery electrolyte and lithium ion battery using same 宁德国泰华荣新材料有限公司 2023-06-30 CN disclosed
CN-110214012-B Azolopyrimidines for the treatment of cancer related disorders 艾库斯生物科学有限公司 2023-05-09 CN disclosed
CN-116072970-A Lithium ion battery electrolyte, lithium ion battery and electric equipment 广汽埃安新能源汽车股份有限公司 2023-05-05 CN disclosed
WO-2019200874-A1 ENGINEERING BACTERIA AND USE THEREOF IN PRODUCTION OF DANSHENSU 江南大学 2019-10-24 WO disclosed
EP-2495323-A1 MODIFIED DOUBLE-STRANDED POLYNUCLEOTIDE Daiichi Sankyo Company, Limited (JP) 2012-09-05 EP disclosed
US-20120220649-A1 MODIFIED DOUBLE-STRANDED POLYNUCLEOTIDE DAIICHI SANKYO COMPANY, LIMITED (JP) 2012-08-30 US disclosed
US-20100310470-A1 IMMUNOMODULATORY POLYMERIC ANTIGENS FOR TREATING INFLAMMATORY PATHOLOGIES TAYLOR KATHLEEN ANN 2010-12-09 US disclosed
US-4810793-A THERMOPLASTIC RESINS THE DOW CHEMICAL COMPANY (US) 1989-03-07 US disclosed
EP-0279207-A2 Composition and method of stabilizing o-halopyridylphosphates DOWELANCO (US) 1988-08-24 EP disclosed
US-4631301-A STABILIZING ON O-PYRIDYL PHOSPHATE INSECTICIDE WITH PHTHALATE ESTERS; FOR CABLES AND PIPELINES DOW CHEMICAL JAPAN LIMITED (JP) 1986-12-23 US disclosed
US-4631301-A STABILIZING ON O-PYRIDYL PHOSPHATE INSECTICIDE WITH PHTHALATE ESTERS; FOR CABLES AND PIPELINES DOW CHEMICAL JAPAN LIMITED (JP) 1986-12-23 US disclosed
US-4083971-A PESTICIDES BASF AKTIENGESELLSCHAFT (DT) 1978-04-11 US disclosed
US-4083971-A PESTICIDES BASF AKTIENGESELLSCHAFT (DT) 1978-04-11 US disclosed
US-4083971-A PESTICIDES BASF AKTIENGESELLSCHAFT (DT) 1978-04-11 US disclosed
US-3928370-A Process for making dialkyl pyridylphosphates DOW CHEMICAL CO 1975-12-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120220649-A1 MODIFIED DOUBLE-STRANDED POLYNUCLEOTIDE POLM, POLN, PNKP SRC 3069/4885FDPS 933/4885KDM4E 4267/4885
US-20100310470-A1 IMMUNOMODULATORY POLYMERIC ANTIGENS FOR TREATING INFLAMMATORY PATHOLOGIES CD47, SPAST, CD74 SRC 1611/4885FDPS 1104/4885KDM4E 4238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.