Hydrochloric Acid

Hydrochloric Acid

SCHEMBL4459246

C[Si](C)=[Zr+2](C1C(c2cccs2)=Cc2ccccc21)C1C(c2cccs2)=Cc2ccccc21.[Cl-].[Cl-]

nearest known ligand 0.31

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 known ✓ P08172 1/20 0.31
CHRM1 known ✓ P11229 1/20 0.31
CHRM3 known ✓ P20309 1/20 0.31
LMNA P02545 3/20 0.31
NPC1 O15118 2/20 0.31
MAPK1 P28482 2/20 0.31
RAB9A P51151 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
ALDH1A1 P00352 1/20 0.31
TP53 P04637 1/20 0.31
NFKB1 P19838 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31
LTA4H P09960 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM5 P08912 1/20 0.31
TDP1 Q9NUW8 1/20 0.30
POLB P06746 1/20 0.30
MEN1 O00255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29459265 1.00 LMNA (0.31) LMNANPC1MAPK1RAB9ASMN1; SMN2
Hydrochloric Acid SCHEMBL965083 0.78 CYP11B1 (0.33)
Hydrochloric Acid SCHEMBL3734166 0.78 CYP11B1 (0.33)
Hydrochloric Acid SCHEMBL5172057 0.74 TNKS2 (0.37) NPC1RAB9ASMN1; SMN2
SCHEMBL7858853 0.73 CHRM2 (0.31) LMNAL3MBTL1ALDH1A1CHRM2CHRM4
Hydrochloric Acid SCHEMBL7064763 0.73 CHRM2 (0.35) LMNANPC1RAB9ASMN1; SMN2L3MBTL1
Hydrochloric Acid SCHEMBL7752884 0.73 CHRM2 (0.35) LMNANPC1RAB9ASMN1; SMN2L3MBTL1
Hydrochloric Acid SCHEMBL339224 0.72
Hydrochloric Acid SCHEMBL966247 0.72
SCHEMBL27709570 0.72 CHRM2 (0.37) LMNANPC1MAPK1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12103987-B2 Method for producing catalyst component for olefin polymerization, method for producing catalyst for olefin polymerization, and method for producing olefin polymer JAPAN POLYPROPYLENE CORPORATION (JP) 2024-10-01 US disclosed
US-20220144978-A1 METHOD FOR PRODUCING CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, METHOD FOR PRODUCING CATALYST FOR OLEFIN POLYMERIZATION, AND METHOD FOR PRODUCING OLEFIN POLYMER JAPAN POLYPROPYLENE CORPORATION (JP) 2022-05-12 US disclosed
EP-3950734-A1 PRODUCTION METHOD FOR CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, PRODUCTION METHOD FOR CATALYST FOR OLEFIN POLYMERIZATION, AND PRODUCTION METHOD FOR OLEFIN POLYMER Japan Polypropylene Corporation (JP) 2022-02-09 EP disclosed
EP-3061774-B1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, AND CATALYST FOR OLEFIN POLYMERIZATION AND PROCESS FOR PRODUCING OLEFIN (CO)POLYMER USING SAME JAPAN POLYPROPYLENE CORP (JP) 2018-04-18 EP disclosed
US-9751961-B2 Catalyst component for olefin polymerization, catalyst for olefin polymerization, and process for producing olefin (co)polymer using the same JAPAN POLYPROPYLENE CORPORATION (JP) 2017-09-05 US disclosed
US-20160272736-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN (CO)POLYMER USING THE SAME JAPAN POLYPROPYLENE CORPORATION (JP) 2016-09-22 US disclosed
US-20090069171-A1 Catalysts for olefin polymerization, process for production of the catalysts, and method for preservation thereof JAPAN POLYPROPYLENE CORPORATION (JP) 2009-03-12 US disclosed
US-6846943-B2 Metallocene compound, olefin polymerization catalyst containing the compound, and method for producing an olefin polymer by use of the catalyst CHISSO CORPORATION (JP) 2005-01-25 US disclosed
EP-1066300-B1 METALLOCENE COMPOUNDS AS CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION CHISSO CORP (JP) 2003-08-20 EP disclosed
US-20010053833-A1 Metallocene compound, olefin polymerization catalyst containing the compound, and method for producing an olefin polymer by use of the catalyst CHISSO CORPORATION (JP) 2001-12-20 US disclosed
US-6326493-B1 COORDINATION CATALYST CHISSO CORPORATION (JP) 2001-12-04 US disclosed