Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 20/20 | 0.69 |
| ▸ | PPARD | Q03181 | 13/20 | 0.69 |
| ▸ | PPARG | P37231 | 11/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4041201 | 0.82 | PPARA (1.00) | PPARAPPARDPPARG | |
| SCHEMBL4454899 | 0.80 | PPARA (0.58) | PPARAPPARDPPARG | |
| SCHEMBL4450745 | 0.80 | PPARA (0.51) | PPARAPPARDPPARG | |
| SCHEMBL4458644 | 0.80 | PPARA (0.67) | PPARAPPARDPPARG | |
| SCHEMBL14122353 | 0.78 | PPARG (0.57) | PPARAPPARG | |
| SCHEMBL15839483 | 0.78 | PPARA (0.56) | PPARAPPARDPPARG | |
| SCHEMBL28622516 | 0.78 | ALOX15 (0.60) | PPARAPPARDPPARG | |
| SCHEMBL8085058 | 0.77 | ALOX5 (0.51) | PPARAPPARG | |
| SCHEMBL10835922 | 0.77 | PPARA (0.56) | PPARAPPARDPPARG | |
| SCHEMBL9070266 | 0.77 | PPARG (0.55) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7482484-B2 | Carboxylic acids and derivatives for the treatment of and preventing diabetes and dyslipidaemia | MERCK PATENT GMBH (DE) | 2009-01-27 | — | — | US | disclosed |