Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9163682 | 0.83 | PPARG (0.43) | GAAPPARAFFAR1PPARGALOX5 | |
| SCHEMBL4458648 | 0.80 | GAA (0.47) | GAAPPARAFFAR1PPARG | |
| SCHEMBL4450871 | 0.77 | GAA (0.54) | GAAFFAR1 | |
| SCHEMBL3658199 | 0.76 | GAA (0.57) | GAAFFAR1TSHR | |
| SCHEMBL3657093 | 0.76 | GAA (0.57) | GAAFFAR1TSHR | |
| SCHEMBL1682681 | 0.76 | GAA (0.77) | GAAFFAR1TSHR | |
| SCHEMBL4449086 | 0.75 | GAA (0.46) | GAAFFAR1 | |
| SCHEMBL3659654 | 0.75 | GAA (0.56) | GAAFFAR1 | |
| SCHEMBL3655663 | 0.75 | GAA (0.56) | GAAFFAR1 | |
| SCHEMBL8085144 | 0.75 | PPARA (0.58) | PPARAPPARGTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7482484-B2 | Carboxylic acids and derivatives for the treatment of and preventing diabetes and dyslipidaemia | MERCK PATENT GMBH (DE) | 2009-01-27 | — | — | US | disclosed |