Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4459435 | 0.80 | GAA (0.48) | GAAFFAR1PPARGPPARA | |
| SCHEMBL4450871 | 0.76 | GAA (0.54) | GAATDP1L3MBTL1FFAR1ALDH1A1 | |
| SCHEMBL3658199 | 0.75 | GAA (0.57) | GAAFFAR1ALDH1A1SMN1; SMN2TNF | |
| SCHEMBL1682681 | 0.75 | GAA (0.77) | GAATDP1FFAR1ALDH1A1CYP3A4 | |
| SCHEMBL3657093 | 0.75 | GAA (0.57) | GAAFFAR1ALDH1A1SMN1; SMN2TNF | |
| SCHEMBL10600889 | 0.75 | GAA (0.67) | GAATDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL8078006 | 0.75 | GAA (0.67) | GAATDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL10599678 | 0.75 | GAA (0.67) | GAATDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL10350216 | 0.75 | ALOX15 (0.55) | GAACYP2C9MEN1KMT2A | |
| SCHEMBL4449086 | 0.74 | GAA (0.46) | GAAFFAR1ALDH1A1SMN1; SMN2TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7482484-B2 | Carboxylic acids and derivatives for the treatment of and preventing diabetes and dyslipidaemia | MERCK PATENT GMBH (DE) | 2009-01-27 | — | — | US | disclosed |