Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4459602 | 1.00 | ALDH1A1 (0.38) | ALDH1A1TDP1FFAR3KDM4EATM | |
| SCHEMBL1669090 | 0.81 | ALDH1A1 (0.40) | ALDH1A1TDP1FFAR3CES2CES1 | |
| SCHEMBL31538698 | 0.77 | CES1 (0.54) | ALDH1A1TDP1CES2CES1TSHR | |
| SCHEMBL10503093 | 0.75 | ALDH1A1 (0.35) | ALDH1A1TDP1FFAR3KDM4EATM | |
| SCHEMBL10503088 | 0.75 | ALDH1A1 (0.35) | ALDH1A1TDP1FFAR3KDM4EATM | |
| SCHEMBL811235 | 0.75 | — | — | |
| SCHEMBL811234 | 0.75 | — | — | |
| Butane SCHEMBL2065960 | 0.74 | HTT (0.39) | ALDH1A1TDP1FFAR3KDM4EATM | |
| Propionamide SCHEMBL27535105 | 0.73 | HTT (0.36) | ALDH1A1TDP1FFAR3KDM4EATM | |
| SCHEMBL676424 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090048461-A1 | Regulators of Bacterial Signalling Pathways | BIOSIGNAL LIMITED (AU) | 2009-02-19 | — | — | US | disclosed |
| EP-1294705-B1 | SYNTHESIS OF CYCLIC COMPOUNDS | BIOSIGNAL LTD (AU) | 2008-09-10 | — | — | EP | disclosed |
| EP-1765755-A4 | REGULATORS OF BACTERIAL SIGNALLING PATHWAYS | BIOSIGNAL LTD (AU) | 2008-05-21 | — | — | EP | disclosed |
| EP-1765755-A1 | REGULATORS OF BACTERIAL SIGNALLING PATHWAYS | Biosignal Limited (AU) | 2007-03-28 | — | — | EP | disclosed |
| WO-2005123645-A1 | REGULATORS OF BACTERIAL SIGNALLING PATHWAYS | BIOSIGNAL LIMITED (AU) | 2005-12-29 | — | — | WO | disclosed |
| US-6958145-B2 | Synthesis of cyclic compounds | UNISEARCH LIMITED (AU) | 2005-10-25 | — | — | US | disclosed |
| EP-1294705-A4 | SYNTHESIS OF CYCLIC COMPOUNDS | UNISEARCH LTD (AU) | 2005-02-09 | — | — | EP | disclosed |
| US-20040110966-A1 | Synthesis of cyclic compounds | UNISEARCH LIMITED (AU) | 2004-06-10 | — | — | US | disclosed |
| EP-1294705-A1 | SYNTHESIS OF CYCLIC COMPOUNDS | UNISEARCH LIMITED (AU) | 2003-03-26 | — | — | EP | disclosed |
| WO-2002000639-A1 | SYNTHESIS OF CYCLIC COMPOUNDS | UNISEARCH LIMITED (AU) | 2002-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048461-A1 | Regulators of Bacterial Signalling Pathways | MRPL21, FNTB, ATF1 | ALDH1A1 4794/4885TDP1 4736/4885FFAR3 2067/4885 |
| US-20040110966-A1 | Synthesis of cyclic compounds | RFC2, POLR2H, REV1 | ALDH1A1 2735/4885TDP1 4404/4885FFAR3 359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.