SCHEMBL4459685

SCHEMBL4459685

CCCCOP(OCCCC)c1ccccc1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.39
CYP1A2 P05177 2/20 0.38
CYP2C9 P11712 2/20 0.38
CYP2C19 P33261 2/20 0.38
TSHR P16473 4/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP19A1 P11511 1/20 0.37
ALDH1A1 P00352 3/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
MITF O75030 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4462349 0.89 TSHR (0.35) TSHRL3MBTL1TDP1ALDH1A1MEN1
SCHEMBL29193848 0.85 LTA4H (0.39) LTA4HCYP1A2CYP2C9CYP2C19TSHR
SCHEMBL4450146 0.82 LTA4H (0.37) LTA4HCYP1A2CYP2C9CYP2C19TSHR
SCHEMBL3727838 0.81 LTA4H (0.36) LTA4HCYP1A2CYP2C9CYP2C19TSHR
SCHEMBL4458090 0.80 TSHR (0.38) TSHRTDP1ALDH1A1MEN1KMT2A
SCHEMBL4461175 0.80 L3MBTL1 (0.40) LTA4HCYP1A2CYP2C9CYP2C19TSHR
SCHEMBL4456016 0.79 LIPG (0.39) LTA4HCYP1A2CYP2C9CYP2C19TSHR
SCHEMBL2938616 0.75 LTA4H (0.47) LTA4HCYP1A2CYP2C9CYP2C19TSHR
SCHEMBL1726278 0.71 CYP2C19 (0.43) LTA4HCYP1A2CYP2C9CYP2C19TSHR
SCHEMBL4460496 0.71 LIPG (0.39) LTA4HCYP2C9CYP2D6CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9511359-B2 Selective hydrogenation catalyst and methods of making and using same CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2016-12-06 US disclosed
US-20160136630-A1 Selective Hydrogenation Catalyst and Methods of Making and Using Same CHEVRON PHILLIPS CHEMICAL COMPANY LP 2016-05-19 US disclosed
US-9221727-B2 Selective hydrogenation catalyst and methods of making and using same CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2015-12-29 US disclosed
US-9012348-B2 Selective hydrogenation catalyst and methods of making and using same CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2015-04-21 US disclosed
US-20140107383-A1 Selective Hydrogenation Catalyst and Methods of Making and Using Same CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2014-04-17 US disclosed
US-7612148-B2 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2009-11-03 US disclosed
US-20080146733-A1 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2008-06-19 US disclosed
US-6818153-B2 Photocurable thermosetting luminescent resins BURNELL-JONES PETER (AU) 2004-11-16 US disclosed
WO-2004011571-A1 PHOTOCURABLE THERMOSETTING LUMINESCENT RESINS ORION 21 A. D. PTY LTD (AU) 2004-02-05 WO disclosed
US-20030085383-A1 For use as gel coat, laminating resin, casting resin or moldable resin; photoluminescent, thermoluminescent and electroluminescent properties BURNELL-JONES PETER (AU) 2003-05-08 US disclosed
US-5410060-A Haloacetylation, carboxylation, phosphination BASF AKTIENGESELLSCHAFT (DE) 1995-04-25 US disclosed
US-4710523-A DISCOLORATION, WEAR RESISTANT SURFACE COATING, FINISHES, AND PRINTING INK BASF AKTIENGESELLSCHAFT (DE) 1987-12-01 US disclosed
US-4324744-A PHOTOINITIATORS BASF AKTIENGESELLSCHAFT (DE) 1982-04-13 US disclosed
US-4298738-A PHOTOINITIATORS IN PHOTOPOLYMERIZABLE COATINGS AND IMKS BASF AKTIENGESELLSCHAFT (DE) 1981-11-03 US disclosed
US-4265723-A UNSATURATED POLYESTERS OR VINYL ESTERS OF POLYEPOXIDES AND A UV SENSITIZER OF AN ACYL PHOSPHINE OXIDE BASF AKTIENGESELLSCHAFT (DE) 1981-05-05 US disclosed