Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4462837 | 0.79 | IGF1R (0.39) | IGF1RKDM5A | |
| SCHEMBL4459043 | 0.73 | IGF1R (0.34) | IGF1R | |
| SCHEMBL4460989 | 0.59 | FGFR2 (0.34) | IGF1R | |
| SCHEMBL3535759 | 0.57 | HRH3 (0.46) | — | |
| SCHEMBL14484041 | 0.57 | HRH3 (0.46) | — | |
| SCHEMBL31080045 | 0.57 | IGF1R (0.57) | IGF1RKDM5A | |
| SCHEMBL31080426 | 0.57 | IGF1R (0.57) | IGF1RKDM5A | |
| SCHEMBL25897972 | 0.57 | HTT (0.46) | — | |
| SCHEMBL30299324 | 0.57 | HTT (0.39) | — | |
| SCHEMBL13452625 | 0.56 | ALDH1A1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009017838-A2 | COMBINATIONS OF JAK-2 INHIBITORS AND OTHER AGENTS | EXELIXIS, INC. (US) | 2009-02-05 | — | — | WO | disclosed |