SCHEMBL4459747

SCHEMBL4459747

O=P(CO)(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.58
L3MBTL1 Q9Y468 2/20 0.50
TDP1 Q9NUW8 1/20 0.50
BTN3A1 O00481 1/20 0.49
KLK8 O60259 2/20 0.47
PLAU P00749 2/20 0.47
KLK2 P20151 2/20 0.47
KLK4 Q9Y5K2 2/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
MEN1 O00255 1/20 0.46
HTT P42858 1/20 0.46
KMT2A Q03164 1/20 0.46
KDM4E B2RXH2 1/20 0.45
ANPEP P15144 2/20 0.44
LAP3 P28838 2/20 0.44
HPGD P15428 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4452187 0.83 SRC (0.54) SRCL3MBTL1TDP1BTN3A1KLK8
SCHEMBL5617330 0.81 SRC (0.56) SRCL3MBTL1TDP1BTN3A1KLK8
SCHEMBL1822019 0.81 SRC (0.56) SRCL3MBTL1TDP1BTN3A1KLK8
SCHEMBL4458081 0.79 SRC (0.50) SRCL3MBTL1TDP1BTN3A1KLK8
SCHEMBL2595713 0.79 SRC (0.54) SRCL3MBTL1TDP1BTN3A1KLK8
SCHEMBL19100687 0.78 SRC (0.59) SRCL3MBTL1TDP1BTN3A1KLK8
SCHEMBL4945259 0.78 SRC (0.54) SRCL3MBTL1TDP1BTN3A1KLK8
SCHEMBL28934305 0.78 SRC (0.54) SRCL3MBTL1TDP1BTN3A1KLK8
SCHEMBL4453721 0.78 SRC (0.48) SRCL3MBTL1TDP1BTN3A1KLK8
SCHEMBL8370393 0.77 SRC (0.52) SRCL3MBTL1TDP1BTN3A1KLK8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112175003-B Preparation method of phenyl hydrogen phosphonate and intermediate thereof 上海医药工业研究院 2022-02-15 CN claimed
CN-112175003-A Preparation method of phenyl hydrogen phosphonate and intermediate thereof 上海医药工业研究院 2021-01-05 CN claimed
CN-111484521-A Phosphorus-containing acrylate flame retardant and preparation method and application thereof 中国科学技术大学 2020-08-04 CN claimed
US-9739063-B2 Roofing systems and roofing boards with non-halogenated fire retardant JOHNS MANVILLE (US) 2017-08-22 US claimed
US-9528269-B2 Roofing systems and roofing boards with non-halogenated fire retardant JOHNS MANVILLE (US) 2016-12-27 US claimed
US-20160348356-A1 ROOFING SYSTEMS AND ROOFING BOARDS WITH NON-HALOGENATED FIRE RETARDANT JOHNS MANVILLE 2016-12-01 US claimed
US-20250242566-A1 FOAM INSULATION WITH IMPROVED LOW TEMPERATURE PROPERTIES USING POLYOL ADDITIVES JOHNS MANVILLE 2025-07-31 US disclosed
CN-115677774-B Phosphonate derivatives, process for their preparation and their use 上海医药工业研究院有限公司 2025-04-22 CN disclosed
US-12012749-B2 Foam insulation with improved low temperature properties using polyol additives JOHNS MANVILLE (US) 2024-06-18 US disclosed
WO-2024107859-A1 CYCLOPENTENE-OXYMETHYLENE PHOSPHONAMIDATES AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS ROME THERAPEUTICS, INC. (US) 2024-05-23 WO disclosed
CN-114409706-B Preparation method of phenyl hydrogen phosphonate and intermediate thereof 上海医药工业研究院 2023-11-28 CN disclosed
US-20230330699-A1 MULTIPLE IMMEDIATE PASS APPLICATION OF HIGH THICKNESS SPRAY FOAMS JOHNS MANVILLE 2023-10-19 US disclosed
US-11717848-B2 Multiple immediate pass application of high thickness spray foams JOHNS MANVILLE (US) 2023-08-08 US disclosed
CN-103073747-A Phosphorus-containing fire retardant and its preparation method JIANGSU YOKE TECHNOLOGY CO LTD 2013-05-01 CN disclosed
US-20120296076-A1 PROCESSES AND INTERMEDIATES FOR PREPARING ANTI-HIV AGENTS GILEAD SCIENCES, INC. 2012-11-22 US disclosed
US-7612148-B2 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2009-11-03 US disclosed
US-20080146733-A1 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2008-06-19 US disclosed
US-6992151-B2 Phosphorus-containing flame-retardant hardener, and epoxy resins cured by the same NATIONAL SCIENCE COUNCIL (TW) 2006-01-31 US disclosed
US-20040024255-A1 Phosphorus-containing flame-retardant hardener, and epoxy resins cured by the same NATIONAL SCIENCE COUNCIL 2004-02-05 US disclosed
US-6613848-B1 Phosphorus-containing phenolic, thiophenolic or aminophenyl flame-retardant hardener, and epoxy resins cured thereby NATIONAL SCIENCE COUNCIL (TW) 2003-09-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120296076-A1 PROCESSES AND INTERMEDIATES FOR PREPARING ANTI-HIV AGENTS SAMHD1, DHPS, LSS SRC 3835/4885L3MBTL1 3662/4885TDP1 1786/4885
US-20040024255-A1 Phosphorus-containing flame-retardant hardener, and epoxy resins cured by the same RBBP4, PPA1, RBBP7 SRC 1199/4885L3MBTL1 4323/4885TDP1 3212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.