Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4447366 | 0.86 | BRD4 (0.36) | BRD4PPARATDP1PPARDPPARG | |
| SCHEMBL4460417 | 0.81 | PPARG (0.39) | PPARAPPARDPPARG | |
| SCHEMBL4458624 | 0.79 | PPARA (0.44) | PPARAPPARDPPARG | |
| SCHEMBL30701777 | 0.77 | HTR2A (0.43) | BRD4MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL27029704 | 0.77 | HTR2A (0.43) | BRD4MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL4460099 | 0.75 | BRD4 (0.64) | BRD4KDM4EKMT2AALDH1A1GAA | |
| SCHEMBL4460104 | 0.74 | BRD4 (0.34) | BRD4PPARAPPARDTHRBPPARG | |
| SCHEMBL7974209 | 0.74 | ABCB1 (0.46) | KDM4EPPARAHTTPPARDALDH1A1 | |
| SCHEMBL10738573 | 0.73 | RAB9A (0.48) | KDM4EMEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL21052075 | 0.72 | MAOB (0.54) | PPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7482484-B2 | Carboxylic acids and derivatives for the treatment of and preventing diabetes and dyslipidaemia | MERCK PATENT GMBH (DE) | 2009-01-27 | — | — | US | disclosed |