Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MGAM | O43451 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SI | P14410 | 2/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13611608 | 0.81 | MAPT (0.44) | S1PR4SLC9A1ALDH1A1RAB9AHPGD | |
| SCHEMBL4460430 | 0.81 | MAPT (0.44) | S1PR4SLC9A1ALDH1A1RAB9AHPGD | |
| SCHEMBL1218954 | 0.78 | SLC9A1 (0.53) | S1PR4SLC9A1ALDH1A1RAB9AHPGD | |
| SCHEMBL4323041 | 0.75 | ALDH1A1 (0.45) | S1PR4ALDH1A1RAB9AHPGDMAPT | |
| SCHEMBL4323030 | 0.75 | ALDH1A1 (0.45) | S1PR4ALDH1A1RAB9AHPGDMAPT | |
| SCHEMBL4460428 | 0.74 | SLC9A1 (0.47) | S1PR4SLC9A1ALDH1A1RAB9AHPGD | |
| SCHEMBL4335881 | 0.73 | ALDH1A1 (0.46) | ALDH1A1RAB9AHPGDMAPTSMN1; SMN2 | |
| SCHEMBL4335875 | 0.73 | ALDH1A1 (0.46) | ALDH1A1RAB9AHPGDMAPTSMN1; SMN2 | |
| SCHEMBL4338967 | 0.73 | HTT (0.50) | ALDH1A1RAB9AHPGDMAPTSMN1; SMN2 | |
| SCHEMBL4338981 | 0.73 | HTT (0.50) | ALDH1A1RAB9AHPGDMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521062-B2 | Thiosemicarbazones as anti-virals and immunopotentiators | NOVARTIS VACCINES & DIAGNOSTICS, INC. (US) | 2009-04-21 | — | — | US | disclosed |