Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4323034 | 0.85 | SLC9A1 (0.41) | SLC9A1ALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL4335877 | 0.82 | LMNA (0.40) | SLC9A1ALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL4338974 | 0.81 | MAPT (0.40) | SLC9A1ALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL4460430 | 0.80 | MAPT (0.44) | SLC9A1ALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL13611608 | 0.80 | MAPT (0.44) | SLC9A1ALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL1218954 | 0.76 | SLC9A1 (0.53) | SLC9A1ALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL4323030 | 0.75 | ALDH1A1 (0.45) | ALDH1A1RAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL4323041 | 0.75 | ALDH1A1 (0.45) | ALDH1A1RAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL4460422 | 0.74 | S1PR4 (0.44) | SLC9A1ALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL4335881 | 0.73 | ALDH1A1 (0.46) | ALDH1A1RAB9AMAPTNPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521062-B2 | Thiosemicarbazones as anti-virals and immunopotentiators | NOVARTIS VACCINES & DIAGNOSTICS, INC. (US) | 2009-04-21 | — | — | US | disclosed |