Betamethasone Dipropionate

SCHEMBL4461054

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nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

NR3C1

The experimentally established mechanism targets of Betamethasone Dipropionate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	NR3C1 known ✓	P04150	8/20	0.81

▸	PGR	P06401	6/20	0.81

▸	ADORA3	P0DMS8	2/20	0.81

▸	NR1I2	O75469	2/20	0.81

▸	MAPT	P10636	2/20	0.81

▸	DRD2	P14416	1/20	0.81

▸	OPRD1	P41143	1/20	0.81

▸	USP2	O75604	5/20	0.76

▸	CYP3A4	P08684	5/20	0.76

▸	HIF1A	Q16665	2/20	0.76

▸	AR	P10275	1/20	0.76

▸	CHRM1	P11229	1/20	0.76

▸	CNR1	P21554	1/20	0.76

▸	TBXA2R	P21731	1/20	0.76

▸	LMNA	P02545	3/20	0.71

▸	CYP2C9	P11712	2/20	0.71

▸	MLNR	O43193	1/20	0.71

▸	ABCB11	O95342	1/20	0.71

▸	CYP3A5	P20815	1/20	0.71

▸	PPARG	P37231	1/20	0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Betamethasone Dipropionate SCHEMBL15876389	0.95	NR3C1 (0.88)	NR3C1PGRADORA3NR1I2MAPT
Beclomethasone Dipropionate SCHEMBL2407947	0.94	CYP3A4 (0.86)	NR3C1PGRADORA3NR1I2MAPT
Beclomethasone Dipropionate SCHEMBL4461051	0.92	NR3C1 (0.90)	NR3C1PGRADORA3NR1I2MAPT
Betamethasone Dipropionate SCHEMBL7520	0.92	NR3C1 (0.95)	NR3C1PGRADORA3NR1I2MAPT
Betamethasone Dipropionate SCHEMBL2403727	0.92	NR3C1 (0.95)	NR3C1PGRADORA3NR1I2MAPT
Betamethasone Dipropionate SCHEMBL515749	0.92	NR3C1 (0.95)	NR3C1PGRADORA3NR1I2MAPT
Betamethasone Dipropionate SCHEMBL1698260	0.91	NR3C1 (0.94)	NR3C1PGRADORA3NR1I2MAPT
SCHEMBL102220	0.91	CYP3A4 (0.83)	NR3C1PGRADORA3NR1I2MAPT
Betamethasone Dipropionate SCHEMBL9768468	0.90	NR3C1 (1.00)	NR3C1PGRADORA3NR1I2MAPT
Betamethasone Dipropionate SCHEMBL11429865	0.90	NR3C1 (1.00)	NR3C1PGRADORA3NR1I2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2009059191-A1	COMPOSITIONS AND METHODS FOR TREATMENT OF EAR CANAL INFECTION AND INFLAMMATION	EVERETT LABORATORIES, INC. (US)	2009-05-07	—	—	WO	claimed