SCHEMBL102220

SCHEMBL102220

CCC(=O)OCC(=O)[C@@]1(OC(=O)CC)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)C3(Cl)[C@@H](OC(=O)CC)C[C@@]21C

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 8/20 0.83
▸ USP2 O75604 7/20 0.83
▸ NR3C1 P04150 6/20 0.83
▸ PGR P06401 6/20 0.83
▸ ADORA3 P0DMS8 3/20 0.83
▸ HIF1A Q16665 2/20 0.83
▸ CNR1 P21554 2/20 0.83
▸ AR P10275 2/20 0.83
▸ CHRM1 P11229 1/20 0.83
▸ TBXA2R P21731 1/20 0.83
▸ NR1I2 O75469 2/20 0.71
▸ MAPT P10636 2/20 0.71
▸ DRD2 P14416 1/20 0.71
▸ OPRD1 P41143 1/20 0.71
▸ LMNA P02545 4/20 0.61
▸ CYP2C9 P11712 3/20 0.61
▸ ABCB11 O95342 3/20 0.61
▸ CYP2D6 P10635 2/20 0.61
▸ MLNR O43193 1/20 0.61
▸ CYP3A5 P20815 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8832311 0.96 CYP3A4 (0.81) CYP3A4USP2NR3C1PGRADORA3
SCHEMBL5516980 0.95 CYP3A4 (0.81) CYP3A4USP2NR3C1PGRADORA3
SCHEMBL1217308 0.95 CYP3A4 (0.77) CYP3A4USP2NR3C1PGRADORA3
Beclomethasone Dipropionate SCHEMBL2407947 0.94 CYP3A4 (0.86) CYP3A4USP2NR3C1PGRADORA3
Water SCHEMBL1219475 0.94 CYP3A4 (0.76) CYP3A4USP2NR3C1PGRADORA3
SCHEMBL13524493 0.94 CYP3A4 (0.83) CYP3A4USP2NR3C1PGRADORA3
SCHEMBL4929631 0.93 CYP3A4 (0.77) CYP3A4USP2NR3C1PGRADORA3
SCHEMBL5319131 0.92 NR3C1 (0.70) CYP3A4USP2NR3C1PGRADORA3
Betamethasone Dipropionate SCHEMBL4461054 0.91 NR3C1 (0.81) CYP3A4USP2NR3C1PGRADORA3
Beclomethasone Dipropionate SCHEMBL5095 0.91 CYP3A4 (1.00) CYP3A4USP2NR3C1PGRADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1095 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4744657-A1 THERAPEUTIC AGENT FOR HUMAN GRAFT VERSUS HOST DISEASE AND COMBINATION THEREOF National University Corporation Okayama University (JP) 2026-05-20 — — EP claimed
EP-4567037-A1 USE OF PYRROLOPYRIMIDINE COMPOUND IN TREATMENT OF ACUTE GRAFT VERSUS HOST DISEASE Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) 2025-06-11 — — EP claimed
CN-120114423-A Beclomethasone dipropionate suspension for inhalation and preparation method thereof 苏州弘森药业股份有限公司 2025-06-10 — — CN claimed
CN-119555851-B Method for measuring in-vitro dissolution curve of suspension for inhalation 上海新黄河制药有限公司 2025-06-03 — — CN claimed
US-20250170069-A1 NANOPREPARATION FOR JOINT ANALGESIA, AND PREPARATION METHOD AND USE THEREOF XIANGYA HOSPITAL CENTRAL SOUTH UNIV (CN) 2025-05-29 — — US claimed
CN-114702594-B Dual specificity antibodies 豪夫迈·罗氏有限公司 2025-05-09 — — CN claimed
CN-119355175-B Method for non-targeted detection of 86 hormone interferents in aquatic ecosystem, hormone interferent ecological risk evaluation method and optimal control sequencing method 成都市食品检验研究院 2025-04-29 — — CN claimed
EP-4541275-A1 ANALYTE SENSOR, AND PREPARATION METHOD THEREFOR AND APPLICATION METHOD THEREOF Shanghai United Imaging Microelectronics Technology Co., Ltd. (CN) 2025-04-23 — — EP claimed
CN-119838022-A Amatoxin conjugates containing branched linkers 杭州多禧生物科技有限公司 2025-04-18 — — CN claimed
US-20250109171-A1 COMPOUNDS AND COMPOSITIONS FOR TARGETED THERAPY OF RENAL DISEASES Shanghai MICURX Pharmaceuticals Co., Ltd. (CN) 2025-04-03 — — US claimed
US-6428804-B1 INJECTABLE MICROCAPSULES CONTAINING BIODEGRADABLE, BIOCOMPAT-IBLE HIGH MOLECULAR WEIGHT POLYMER AND THERAPEUTIC DRUG SUS-PENDED IN HYALURONIC ACID AND/OR CHONDROITIN SULFATE MEDIUM; INHIBITS SIDE EFFECTS; LONG TERM EFFICACY SSP CO., LTD. (JP) 2002-08-06 — — US claimed
US-6197326-B1 ADMINISTERING HYALURONIC ACID, CHONDROITIN SULFATE AND SALTS BY INJECTION FOR JOINT PAIN SSP CO., LTD. (JP) 2001-03-06 — — US claimed
US-5897878-A ORALLY ADMINISTERING DELIVERY SYSTEM IN WHICH FLUID IMBIBITION CAUSES HYDROPHILIC POLYMER TO AGGREGATE IN SITU IN PRESENCE OF POLYHYDROXY COMPOUND AND CAUSES PUSH LAYER TO ABSORB FLUID AND DELIVER AGGREGATES CONTAINING STEROID ALZA CORPORATION (US) 1999-04-27 — — US claimed
US-5650170-A Dosage form for delivering drug at a controlled rate to the intestine and to the colon ALZA CORPORATION (US) 1997-07-22 — — US claimed
EP-0521074-B1 DOSAGE FORM FOR DELIVERING DRUG TO THE INTESTINE ALZA CORP (US) 1994-03-02 — — EP claimed
US-5178866-A DOSAGE FORM FOR DELIVERING DRUG TO THE INTESTINE ALZA CORPORATION (US) 1993-01-12 — — US claimed
EP-0521074-A1 DOSAGE FORM FOR DELIVERING DRUG TO THE INTESTINE. ALZA CORP (US) 1993-01-07 — — EP claimed
WO-1991014426-A1 DOSAGE FORM FOR DELIVERING DRUG TO THE INTESTINE ALZA CORPORATION (US) 1991-10-03 — — WO claimed
US-4879274-A IMPROVED ABSORPTION KAO CORPORATION (JP) 1989-11-07 — — US claimed
US-4765983-A INTESTINAL-SOLUBLE POLYMER AND MEDICAMENT YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1988-08-23 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250109171-A1 COMPOUNDS AND COMPOSITIONS FOR TARGETED THERAPY OF RENAL DISEASES REN, VHL, RCC2 CYP3A4 4216/4885USP2 3875/4885NR3C1 3381/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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