Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4461101 | 1.00 | TSHR (0.47) | TSHRGAATRPV1MAPTNPC1 | |
| SCHEMBL4458084 | 0.83 | TRPV1 (0.44) | GAATRPV1 | |
| SCHEMBL4458089 | 0.83 | TRPV1 (0.44) | GAATRPV1 | |
| SCHEMBL4465905 | 0.83 | TRPV1 (0.44) | GAATRPV1 | |
| SCHEMBL4327380 | 0.77 | TRPV1 (0.73) | TRPV1 | |
| SCHEMBL4327376 | 0.77 | TRPV1 (0.73) | TRPV1 | |
| SCHEMBL13783793 | 0.75 | TRPV1 (0.52) | GAATRPV1HSD11B1 | |
| SCHEMBL4319487 | 0.72 | TRPV1 (0.53) | GAATRPV1MAPTHSD11B1 | |
| SCHEMBL4319481 | 0.72 | TRPV1 (0.53) | GAATRPV1MAPTHSD11B1 | |
| SCHEMBL4320157 | 0.66 | EPHX2 (0.56) | TSHRGAATRPV1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |