Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.44 |
| ▸ | BLM | P54132 | 5/20 | 0.42 |
| ▸ | HPN | P05981 | 1/20 | 0.40 |
| ▸ | WRN | Q14191 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4458089 | 1.00 | TRPV1 (0.44) | TRPV1BLMHPNWRNGAA | |
| SCHEMBL4458084 | 1.00 | TRPV1 (0.44) | TRPV1BLMHPNWRNGAA | |
| SCHEMBL4461106 | 0.83 | TSHR (0.47) | TRPV1GAA | |
| SCHEMBL4461101 | 0.83 | TSHR (0.47) | TRPV1GAA | |
| SCHEMBL4327380 | 0.75 | TRPV1 (0.73) | TRPV1 | |
| SCHEMBL4327376 | 0.75 | TRPV1 (0.73) | TRPV1 | |
| SCHEMBL13783793 | 0.73 | TRPV1 (0.52) | TRPV1GAAHCRTR1HCRTR2 | |
| SCHEMBL4319487 | 0.70 | TRPV1 (0.53) | TRPV1GAA | |
| SCHEMBL4319481 | 0.70 | TRPV1 (0.53) | TRPV1GAA | |
| SCHEMBL4320157 | 0.65 | EPHX2 (0.56) | TRPV1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | claimed |