Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 5/20 | 0.47 |
| ▸ | PLAU | P00749 | 5/20 | 0.47 |
| ▸ | F10 | P00742 | 5/20 | 0.47 |
| ▸ | F2 | P00734 | 4/20 | 0.47 |
| ▸ | ST14 | Q9Y5Y6 | 4/20 | 0.47 |
| ▸ | PARP1 | P09874 | 2/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.41 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7563815 | 0.81 | SIGMAR1 (0.50) | SIGMAR1 | |
| SCHEMBL4461405 | 0.76 | PRSS1 (0.61) | PLGPLAUF10F2PRSS1 | |
| SCHEMBL7118456 | 0.72 | PRSS1 (0.64) | PLAUF10F2PRSS1PRSS2 | |
| SCHEMBL27554554 | 0.71 | PRSS1 (0.47) | PLGPLAUF10F2ST14 | |
| SCHEMBL27392418 | 0.69 | PRSS1 (0.51) | PLAUF10F2PRSS1PRSS2 | |
| SCHEMBL19990975 | 0.69 | PRSS1 (0.65) | PLGPLAUF10F2PRSS1 | |
| SCHEMBL1763270 | 0.69 | SIGMAR1 (0.61) | PARP1SIGMAR1 | |
| SCHEMBL9257484 | 0.68 | SIGMAR1 (0.60) | PARP1SIGMAR1 | |
| SCHEMBL15986678 | 0.68 | SIGMAR1 (0.59) | PARP1SIGMAR1 | |
| SCHEMBL30799020 | 0.68 | SLC6A4 (0.58) | SLC6A4SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0635008-B1 | PIPERAZIDES OF SUBSTITUTED PHENYLALANINE DERIVATES AS THROMBIN INHIBITORS | PENTAPHARM AG (CH) | 2002-09-04 | — | — | EP | disclosed |