Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7639376 | 0.87 | MAPT (0.42) | MAPTPOLBL3MBTL1TP53HPGD | |
| SCHEMBL31255615 | 0.82 | MAPT (0.49) | MAPTPOLBL3MBTL1TP53HPGD | |
| SCHEMBL6155076 | 0.80 | LMNA (0.51) | MAPTPOLBL3MBTL1TP53HPGD | |
| Methyl Alcohol SCHEMBL28904294 | 0.79 | LMNA (0.50) | MAPTPOLBTP53HPGDCYP1A2 | |
| SCHEMBL13645117 | 0.78 | ALDH1A1 (0.56) | MAPTPOLBL3MBTL1HPGDCYP1A2 | |
| SCHEMBL7637797 | 0.78 | HPGD (0.60) | MAPTTP53HPGDCYP1A2CYP2C19 | |
| SCHEMBL13170447 | 0.75 | CNR1 (0.41) | MAPTPOLBTP53KDM4EHTT | |
| SCHEMBL31255482 | 0.75 | HPGD (0.45) | MAPTPOLBTP53HPGDCYP1A2 | |
| SCHEMBL7639373 | 0.75 | MAPT (0.42) | MAPTPOLBL3MBTL1TP53HPGD | |
| SCHEMBL12304995 | 0.74 | PTGS1 (0.45) | MAPTPOLBL3MBTL1TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1791852-B8 | C-ARYL GLUCOSIDE SGLT2 INHIBITORS AND METHOD FOR THEIR PRODUCTION | BRISTOL MYERS SQUIBB CO (US) | 2009-04-01 | — | — | EP | disclosed |
| EP-1791852-A2 | C-ARYL GLUCOSIDE SGLT2 INHIBITORS AND METHOD FOR THEIR PRODUCTION | Brystol-Myers Squibb Company (US) | 2007-06-06 | — | — | EP | disclosed |
| WO-2006034489-A2 | C-ARYL GLUCOSIDE SGLT2 INHIBITORS AND METHOD FOR THEIR PRODUCTION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-03-30 | — | — | WO | disclosed |