Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL28904294 | 0.99 | LMNA (0.50) | LMNAMAPTMEN1KMT2ARAB9A | |
| SCHEMBL29022661 | 0.85 | LMNA (0.57) | LMNAMAPTMEN1KMT2ARAB9A | |
| SCHEMBL5044303 | 0.85 | MAPT (0.50) | LMNAMAPTMEN1KMT2ARAB9A | |
| SCHEMBL7637797 | 0.85 | HPGD (0.60) | LMNAMAPTKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9984540 | 0.83 | TSHR (0.61) | LMNAMAPTMEN1KMT2ARAB9A | |
| SCHEMBL14248500 | 0.81 | MAPT (0.56) | MAPTKMT2ARAB9AALDH1A1HPGD | |
| SCHEMBL4461435 | 0.80 | MAPT (0.43) | LMNAMAPTSMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL31255615 | 0.78 | MAPT (0.49) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL30033997 | 0.78 | RAB9A (0.67) | LMNAMAPTMEN1KMT2ARAB9A | |
| SCHEMBL720460 | 0.78 | RAB9A (0.67) | LMNAMAPTMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115445242-B | Device and method for treating dapagliflozin intermediate mother liquor | 浙江工业大学 | 2024-03-01 | — | — | CN | claimed |
| CN-115445242-A | Treatment device and method for dapagliflozin intermediate mother liquor | 浙江工业大学 | 2022-12-09 | — | — | CN | claimed |
| CN-107311847-B | Preparation method of 5-bromo-2-chloro-4' -ethoxy diphenylmethane | 安徽省诚联医药科技有限公司 | 2020-11-10 | — | — | CN | claimed |
| CN-111662166-A | Preparation method of 5-bromo-2-chloro-4' -ethoxy diphenylmethane | 吴赣药业（苏州）有限公司 | 2020-09-15 | — | — | CN | claimed |
| CN-115445242-B | Device and method for treating dapagliflozin intermediate mother liquor | 浙江工业大学 | 2024-03-01 | — | — | CN | disclosed |
| CN-115445242-B | Device and method for treating dapagliflozin intermediate mother liquor | 浙江工业大学 | 2024-03-01 | — | — | CN | disclosed |
| CN-116332733-A | Synthesis process of dapagliflozin intermediate | 江苏阿尔法药业股份有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-115445242-A | Treatment device and method for dapagliflozin intermediate mother liquor | 浙江工业大学 | 2022-12-09 | — | — | CN | disclosed |
| CN-115445242-A | Treatment device and method for dapagliflozin intermediate mother liquor | 浙江工业大学 | 2022-12-09 | — | — | CN | disclosed |
| CN-107311847-B | Preparation method of 5-bromo-2-chloro-4' -ethoxy diphenylmethane | 安徽省诚联医药科技有限公司 | 2020-11-10 | — | — | CN | disclosed |
| CN-107311847-B | Preparation method of 5-bromo-2-chloro-4' -ethoxy diphenylmethane | 安徽省诚联医药科技有限公司 | 2020-11-10 | — | — | CN | disclosed |
| CN-111662166-A | Preparation method of 5-bromo-2-chloro-4' -ethoxy diphenylmethane | 吴赣药业（苏州）有限公司 | 2020-09-15 | — | — | CN | disclosed |
| CN-111662166-A | Preparation method of 5-bromo-2-chloro-4' -ethoxy diphenylmethane | 吴赣药业（苏州）有限公司 | 2020-09-15 | — | — | CN | disclosed |
| CN-111099975-A | Preparation method of 5-bromo-2-chloro-4' -ethoxy benzophenone | 河北合佳医药科技集团股份有限公司 | 2020-05-05 | — | — | CN | disclosed |
| EP-1506211-A4 | C-ARYL GLUCOSIDE SGLT2 INHIBITORS AND METHOD | BRISTOL MYERS SQUIBB CO (US) | 2005-08-17 | — | — | EP | disclosed |
| EP-1506211-A1 | C-ARYL GLUCOSIDE SGLT2 INHIBITORS AND METHOD | Bristol-Myers Squibb Company (US) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003099836-A1 | C-ARYL GLUCOSIDE SGLT2 INHIBITORS AND METHOD | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-12-04 | — | — | WO | disclosed |