SCHEMBL4461646

SCHEMBL4461646

CC(=O)c1ccc(OCC2CO2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.57
ALDH1A1 P00352 4/20 0.57
LMNA P02545 4/20 0.57
TP53 P04637 3/20 0.57
TSHR P16473 3/20 0.57
HPGD P15428 3/20 0.57
GAA P10253 2/20 0.57
PKM P14618 2/20 0.57
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
HIF1A Q16665 2/20 0.57
CYP1A2 P05177 1/20 0.57
PPARG P37231 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
SMN1; SMN2 Q16637 4/20 0.53
MAOB P27338 3/20 0.53
POLB P06746 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
CYP3A4 P08684 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10350981 0.86 ALDH1A1 (0.60) MAPTALDH1A1LMNATP53TSHR
SCHEMBL10350238 0.86 ALDH1A1 (0.60) MAPTALDH1A1LMNATP53TSHR
SCHEMBL12517400 0.86 ALDH1A1 (0.60) MAPTALDH1A1LMNATP53TSHR
SCHEMBL27603639 0.86 ALDH1A1 (0.60) MAPTALDH1A1LMNATP53TSHR
SCHEMBL24595171 0.85 L3MBTL1 (0.59) MAPTALDH1A1LMNATSHRGAA
SCHEMBL14111306 0.85 L3MBTL1 (0.64) MAPTALDH1A1LMNATSHRGAA
SCHEMBL11967035 0.85 L3MBTL1 (0.55) MAPTALDH1A1LMNATP53TSHR
SCHEMBL11967034 0.85 L3MBTL1 (0.55) MAPTALDH1A1LMNATP53TSHR
SCHEMBL8120865 0.85 TDP1 (0.62) MAPTALDH1A1LMNATP53TSHR
SCHEMBL2449453 0.85 TDP1 (0.62) MAPTALDH1A1LMNATP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116730954-A Isopropanolamine compound containing chalcone structure, and preparation method and application thereof 贵州大学 2023-09-12 CN disclosed
US-20210347962-A1 COMPOSITIONS COMPRISING ESTOLIDE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME BIOSYNTHETIC TECHNOLOGIES, LLC (US) 2021-11-11 US disclosed
US-20190292350-A1 COMPOSITIONS COMPRISING ESTOLIDE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME BIOSYNTHETIC TECHNOLOGIES LLC (US) 2019-09-26 US disclosed
US-10240025-B2 Compositions comprising estolide compounds and methods of making and using the same BIOSYNTHETIC TECHNOLOGIES, LLC (US) 2019-03-26 US disclosed
US-20180112060-A1 COMPOSITIONS COMPRISING ESTOLIDE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME BIOSYNTHETIC TECHNOLOGIES LLC (US) 2018-04-26 US disclosed
US-9840606-B2 Compositions comprising estolide compounds and methods of making and using the same BIOSYNTHETIC TECHNOLOGIES, LLC (US) 2017-12-12 US disclosed
US-20170292006-A1 COMPOSITIONS COMPRISING ESTOLIDE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME BIOSYNTHETIC TECHNOLOGIES LLC (US) 2017-10-12 US disclosed
US-9637700-B2 Compositions comprising estolide compounds and methods of making and using the same BIOSYNTHETIC TECHNOLOGIES, LLC (US) 2017-05-02 US disclosed
US-9546336-B2 Compositions comprising estolide compounds and methods of making and using the same BIOSYNTHETIC TECHNOLOGIES, LLC. (US) 2017-01-17 US disclosed
US-9487725-B2 Compositions comprising estolide compounds and methods of making and using the same BIOSYNTHETIC TECHNOLOGIES, LLC. (US) 2016-11-08 US disclosed
EP-0994148-A1 A pleasantly fragrant process for stabilizing halogen-containing polymers MORTON INTERNATIONAL, INC. (US) 2000-04-19 EP disclosed
EP-0056486-B1 PHENYLPIPERAZINYL-PROPANOLES OF HETARYLPHENOLS, THEIR PREPARATION AND THEIR PHARMACEUTICAL COMPOSITIONS BASF Aktiengesellschaft (DE) 1985-11-06 EP disclosed
US-4428950-A HYPOTENSIVES, SEDATIVES, NEUROLEPTICS AND BRONCHOLYTICS BASF AKTIENGESELLSCHAFT (DE) 1984-01-31 US disclosed
US-4342875-A STABILIZERS FOR OLEFIN POLYMERS CINCINNATI-MILACRON, INC. (US) 1982-08-03 US disclosed
EP-0056486-A2 Phenylpiperazinyl-propanoles of hetarylphenols, their preparation and their pharmaceutical compositions BASF Aktiengesellschaft (DE) 1982-07-28 EP disclosed
US-RE29523-E Olefinic polymers stabilized with thioacyl trivalent phosphorus compounds BORG-WARNER CORPORATION (US) 1978-01-24 US disclosed
US-4064100-A HEAT AND LIGHT STABILIZERS FOR POLYMERS, CONTAINERS FOR FOOD WESTON CHEMICAL CO., INC. (US) 1977-12-20 US disclosed
US-4012399-A ULTRAVIOLET LIGHT ABSORBERS AND STABILIZERS CINCINNATI MILACRON CHEMICALS, INC. (US) 1977-03-15 US disclosed
US-4000101-A POLYPROPYLENE WESTON CHEMICAL CORPORATION (US) 1976-12-28 US disclosed
US-3959220-A Polymer additives comprising transition metal complexes with trivalent phosphorous compounds CINCINNATI MILACRON CHEMICALS, INC. (US) 1976-05-25 US disclosed