Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7352199 | 0.72 | SMN1; SMN2 (0.48) | GAASMN1; SMN2ALDH1A1PKMMAPT | |
| SCHEMBL7220797 | 0.69 | ACACB (0.46) | SMN1; SMN2ACACBMAPTHTTF2RL1 | |
| SCHEMBL9166221 | 0.69 | PPARA (0.50) | GAASMN1; SMN2ALDH1A1PKMMAPT | |
| SCHEMBL7334996 | 0.68 | GAA (0.57) | GAASMN1; SMN2ALDH1A1PKMMAPT | |
| SCHEMBL5410393 | 0.68 | GAA (0.61) | GAASMN1; SMN2ALDH1A1PKMMAPT | |
| SCHEMBL62037 | 0.66 | IDO1 (0.59) | GAASMN1; SMN2ALDH1A1MAOBMAOA | |
| SCHEMBL7216025 | 0.66 | ALDH1A1 (0.42) | GAASMN1; SMN2ALDH1A1PKMACACB | |
| SCHEMBL13953042 | 0.66 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1ACACBMAPTF2RL1 | |
| SCHEMBL11490960 | 0.66 | IDO1 (0.47) | GAASMN1; SMN2ALDH1A1MAOBMAOA | |
| SCHEMBL16341200 | 0.66 | ACACB (0.60) | SMN1; SMN2ACACBHTTF2RL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |