SCHEMBL4462189

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29580874	0.82	MEN1 (0.48)	ALDH1A1HPGDSMN1; SMN2MEN1KMT2A
	SCHEMBL29421049	0.81	PDE4C (0.49)	ALDH1A1HPGDSMN1; SMN2MEN1KMT2A
	SCHEMBL762311	0.79	NR4A2 (0.62)	NR4A2ALDH1A1HPGDSMN1; SMN2MAPK13
	SCHEMBL29154651	0.76	MAPK13 (0.60)	NR4A2ALDH1A1HPGDSMN1; SMN2MEN1
	SCHEMBL7808125	0.74	USP1 (0.61)	ALDH1A1HPGDSMN1; SMN2MEN1KMT2A
	SCHEMBL22761529	0.73	NR4A2 (0.55)	NR4A2ALDH1A1HPGDSMN1; SMN2MEN1
	SCHEMBL7059841	0.73	ALDH1A1 (0.73)	ALDH1A1HPGDSMN1; SMN2MEN1KMT2A
	Dimethylamine SCHEMBL8172161	0.73	MAPK13 (0.56)	NR4A2ALDH1A1HPGDSMN1; SMN2MAPK13
	SCHEMBL23949970	0.72	ALDH1A1 (0.55)	ALDH1A1HPGDSMN1; SMN2MEN1KMT2A
	SCHEMBL6958523	0.70	NPC1 (0.66)	NR4A2ALDH1A1HPGDSMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.