Linolenic Acid

Linolenic Acid

SCHEMBL446226

CC/C=C\C/C=C\C/C=C\CCCCCCCC(=O)[O-].CC/C=C\C/C=C\C/C=C\CCCCCCCC(=O)[O-].[Ca+2]

nearest known ligand 0.96

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Linolenic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 known ✓ P23219 2/20 0.69
PTGS2 known ✓ P35354 1/20 0.69
FABP3 P05413 9/20 0.96
ALDH1A1 P00352 5/20 0.69
F7 P08709 3/20 0.69
F3 P13726 3/20 0.69
CYP19A1 P11511 3/20 0.69
MAPT P10636 2/20 0.69
CYP3A4 P08684 2/20 0.69
ALOX15 P16050 2/20 0.69
HSD17B10 Q99714 2/20 0.69
TDP1 Q9NUW8 2/20 0.69
OXER1 Q8TDS5 2/20 0.69
PPARG P37231 2/20 0.69
KMT2A Q03164 2/20 0.69
PPARD Q03181 2/20 0.69
PPARA Q07869 2/20 0.69
KDM4E B2RXH2 1/20 0.69
MEN1 O00255 1/20 0.69
FFAR1 O14842 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Linolenic Acid SCHEMBL666389 0.96 FABP3 (0.96) FABP3ALDH1A1F7F3CYP19A1
Linolenic Acid SCHEMBL4853105 0.96 FABP3 (0.96) FABP3ALDH1A1F7F3CYP19A1
Linolenic Acid SCHEMBL6140641 0.96 FABP3 (0.96) FABP3ALDH1A1F7F3CYP19A1
Linolenic Acid SCHEMBL4918659 0.96 FABP3 (0.96) FABP3ALDH1A1F7F3CYP19A1
Linolenic Acid SCHEMBL2410422 0.96 FABP3 (0.96) FABP3ALDH1A1F7F3CYP19A1
SCHEMBL25403260 0.96 FABP3 (0.96) FABP3ALDH1A1F7F3CYP19A1
Linolenic Acid SCHEMBL4409873 0.96 FABP3 (0.96) FABP3ALDH1A1F7F3CYP19A1
Linolenic Acid SCHEMBL4921337 0.96 FABP3 (0.96) FABP3ALDH1A1F7F3CYP19A1
Linolenic Acid SCHEMBL11594359 0.96 FABP3 (0.96) FABP3ALDH1A1F7F3CYP19A1
Linolenic Acid SCHEMBL539075 0.96 FABP3 (0.96) FABP3ALDH1A1F7F3CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111280317-A Functional additive, preparation method and application thereof, and lactating ewe feed containing functional additive 广州市优百特饲料科技有限公司 2020-06-16 CN claimed
CN-110214893-A Full nutritious food of linseed bean powder and preparation method thereof 广西南宁市康之豆食品科技有限责任公司 2019-09-10 CN claimed
CN-103803489-B The preparation method of large scale hydroxyapatite micrometre tube oldered array SHANGHAI INSTITUTE OF CERAMICS, CHINESE ACADEMY OF SCIENCES (CN) 2015-10-21 CN claimed
CN-103803489-A Preparation method of large-size hydroxyl apatite microtube ordered array SHANGHAI INST CERAMICS 2014-05-21 CN claimed
EP-0319203-A2 Improvements in materials for the manufacture of fiber-reinforced thermosetting resin mouldings MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-06-07 EP claimed
US-20240308109-A1 NUCLEATING AGENT COMPOSITION, RESIN COMPOSITION, MOLDED ARTICLE THEREOF, AND METHOD FOR MANUFACTURING RESIN COMPOSITION ADEKA CORPORATION (JP) 2024-09-19 US disclosed
CN-115926502-B Non-stick material, preparation method thereof and non-stick coating 武汉苏泊尔炊具有限公司 2024-09-06 CN disclosed
EP-3689590-B1 LAYERED TUBE UBE CORP (JP) 2024-08-28 EP disclosed
US-12045000-B2 Image forming apparatus RICOH COMPANY, LTD. (JP) 2024-07-23 US disclosed
CN-111796495-B Electrophotographic image forming method and electrophotographic image forming system 柯尼卡美能达株式会社 2024-07-02 CN disclosed
EP-4357405-A1 NUCLEATING AGENT COMPOSITION, RESIN COMPOSITION, MOLDED ARTICLE THEREOF, AND METHOD FOR MANUFACTURING RESIN COMPOSITION ADEKA CORPORATION (JP) 2024-04-24 EP disclosed
CN-117580906-A Nucleating agent composition, resin composition, molded article thereof, and method for producing resin composition 株式会社ADEKA 2024-02-20 CN disclosed
US-6813458-B2 Image forming apparatus SEIKO EPSON CORPORATION (JP) 2004-11-02 US disclosed
EP-1306731-A2 Cleanerless image forming apparatus and toner particles coated with external additives SEIKO EPSON CORPORATION (JP) 2003-05-02 EP disclosed
US-20030063922-A1 Image forming apparatus SEIKO EPSON CORPORATION 2003-04-03 US disclosed
CN-1235020-A Medicinal products of superfined alpha-linolenic acid, preparing process and preparation thereof LI WENGUANG (CN) 1999-11-17 CN disclosed
US-5510886-A Image forming apparatus having an intermediate image carrier RICOH COMPANY, LTD. (JP) 1996-04-23 US disclosed
EP-0319203-A2 Improvements in materials for the manufacture of fiber-reinforced thermosetting resin mouldings MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-06-07 EP disclosed
US-4705515-A Dosage form for administering drug of the colon ALZA CORPORATION (US) 1987-11-10 US disclosed
US-4627851-A Colonic-therapeutic delivery system ALZA CORPORATION (US) 1986-12-09 US disclosed