SCHEMBL4462408

SCHEMBL4462408

CC(C)[Si](C#Cc1c2ccccc2c(C#C[Si](C(C)C)(C(C)C)C(C)C)c2ccccc12)(C(C)C)C(C)C

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CACNA2D1 P54289 1/20 0.41
CACNB2 Q08289 1/20 0.41
CACNA1C Q13936 1/20 0.41
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
HSD17B10 Q99714 1/20 0.31
MAPT P10636 1/20 0.30
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30
CASP1 P29466 1/20 0.30
CASP7 P55210 1/20 0.30
ATM Q13315 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29537640 1.00 CACNA2D1 (0.41) CACNA2D1CACNB2CACNA1CALDH1A1HPGD
SCHEMBL10090590 0.94 CACNA2D1 (0.38) CACNA2D1CACNB2CACNA1C
SCHEMBL715009 0.91 CACNA2D1 (0.39) CACNA2D1CACNB2CACNA1C
SCHEMBL10022715 0.91 CACNA2D1 (0.39) CACNA2D1CACNB2CACNA1C
SCHEMBL30360377 0.89 CACNA2D1 (0.35) CACNA2D1CACNB2CACNA1CALDH1A1HSD17B10
SCHEMBL14514097 0.89 CACNA2D1 (0.35) CACNA2D1CACNB2CACNA1CALDH1A1HSD17B10
SCHEMBL23166655 0.86 CACNA2D1 (0.33) CACNA2D1CACNB2CACNA1CALDH1A1
SCHEMBL651091 0.86 CACNA2D1 (0.33) CACNA2D1CACNB2CACNA1CALDH1A1HSD17B10
SCHEMBL28711746 0.85 CACNA2D1 (0.35) CACNA2D1CACNB2CACNA1CALDH1A1HPGD
SCHEMBL29531808 0.85 CACNA2D1 (0.35) CACNA2D1CACNB2CACNA1CALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118085850-B Temperature ratio fluorescent probe based on triplet state-triplet state annihilation up-conversion luminescence and preparation method and application thereof 中国科学院理化技术研究所 2024-07-16 CN claimed
CN-118085850-A Temperature ratio fluorescent probe based on triplet state-triplet state annihilation up-conversion luminescence and preparation method and application thereof 中国科学院理化技术研究所 2024-05-28 CN claimed
US-12291662-B2 Photon upconversion nanocapsules for 3D printing and other applications PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2025-05-06 US disclosed
CN-118085850-B Temperature ratio fluorescent probe based on triplet state-triplet state annihilation up-conversion luminescence and preparation method and application thereof 中国科学院理化技术研究所 2024-07-16 CN disclosed
CN-118085850-A Temperature ratio fluorescent probe based on triplet state-triplet state annihilation up-conversion luminescence and preparation method and application thereof 中国科学院理化技术研究所 2024-05-28 CN disclosed
EP-3887480-B1 PHOTON UPCONVERSION NANOCAPSULES FOR 3D PRINTING AND OTHER APPLICATIONS HARVARD COLLEGE (US) 2024-02-14 EP disclosed
US-20230357630-A1 HEAVY-ATOM FREE SENSITIZERS FOR TRIPLET-TRIPLET ANNIHILATION UPCONVERSION SYSTEMS UNIVERSITY OF WASHINGTON (US) 2023-11-09 US disclosed
US-20220025255-A1 PHOTON UPCONVERSION NANOCAPSULES FOR 3D PRINTING AND OTHER APPLICATIONS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2022-01-27 US disclosed
WO-2021067577-A1 HEAVY ATOM-FUNCTIONALIZED UPCONVERTERS FOR INCREASING UPCONVERSION THRESHOLDS FOR 3D PRINTING PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2021-04-08 WO disclosed
US-20180102222-A1 PHOTOELECTRIC CONVERSION ELEMENT, AND SOLAR CELL USING THE SAME FUJIFILM CORPORATION (JP) 2018-04-12 US disclosed
US-20180102222-A1 PHOTOELECTRIC CONVERSION ELEMENT, AND SOLAR CELL USING THE SAME FUJIFILM CORPORATION (JP) 2018-04-12 US disclosed
US-9281485-B2 Light-receiving device SHARP KABUSHIKI KAISHA (JP) 2016-03-08 US disclosed
US-20150155509-A1 LIGHT-RECEIVING DEVICE SHARP KABUSHIKI KAISHA (JP) 2015-06-04 US disclosed
EP-2011157-A4 ELECTRONIC DEVICES CONTAINING ACENE-THIOPHENE COPOLYMERS WITH SILYLETHYNYL GROUPS 3M INNOVATIVE PROPERTIES CO (US) 2009-05-06 EP disclosed
EP-2011157-A1 ELECTRONIC DEVICES CONTAINING ACENE-THIOPHENE COPOLYMERS WITH SILYLETHYNYL GROUPS 3M Innovative Properties Company (US) 2009-01-07 EP disclosed
WO-2007124286-A1 ELECTRONIC DEVICES CONTAINING ACENE-THIOPHENE COPOLYMERS WITH SILYLETHYNYL GROUPS 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-11-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357630-A1 HEAVY-ATOM FREE SENSITIZERS FOR TRIPLET-TRIPLET ANNIHILATION UPCONVERSION SYSTEMS SLC6A4, TST, SLC6A6 CACNA2D1 4442/4885CACNB2 2987/4885CACNA1C 4131/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.