SCHEMBL715009

SCHEMBL715009

CC(C)[Si](C#Cc1c2ccccc2c2ccc3c(C#C[Si](C(C)C)(C(C)C)C(C)C)c4ccccc4c4ccc1c2c34)(C(C)C)C(C)C

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CACNA2D1 P54289 1/20 0.39
CACNB2 Q08289 1/20 0.39
CACNA1C Q13936 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10022715 1.00 CACNA2D1 (0.39) CACNA2D1CACNB2CACNA1C
SCHEMBL4462408 0.91 CACNA2D1 (0.41) CACNA2D1CACNB2CACNA1C
SCHEMBL29537640 0.91 CACNA2D1 (0.41) CACNA2D1CACNB2CACNA1C
SCHEMBL717351 0.88 CACNA2D1 (0.34) CACNA2D1CACNB2CACNA1C
SCHEMBL10090590 0.85 CACNA2D1 (0.38) CACNA2D1CACNB2CACNA1C
SCHEMBL10034265 0.85 BCHE (0.32) CACNA2D1CACNB2CACNA1C
SCHEMBL17231135 0.83 CACNA2D1 (0.36) CACNA2D1CACNB2CACNA1C
SCHEMBL21821368 0.83 CYP1A2 (0.33) CACNA2D1CACNB2CACNA1C
SCHEMBL718325 0.81 ALDH1A1 (0.31)
SCHEMBL14514097 0.81 CACNA2D1 (0.35) CACNA2D1CACNB2CACNA1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2649082-B1 NON-LINEAR ACENE DERIVATIVES AND THEIR USE AS ORGANIC SEMICONDUCTORS MERCK PATENT GMBH (DE) 2015-01-14 EP disclosed
US-20130248771-A1 NON-LINEAR ACENE DERIVATIVES AND THEIR USE AS ORGANIC SEMICONDUCTORS MERCK PATENT GMBH (DE) 2013-09-26 US disclosed
US-20120048377-A1 PHOTOSENSITIVE OPTOELECTRONIC DEVICES COMPRISING POLYCYCLIC AROMATIC COMPOUNDS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2012-03-01 US disclosed
US-20120048377-A1 PHOTOSENSITIVE OPTOELECTRONIC DEVICES COMPRISING POLYCYCLIC AROMATIC COMPOUNDS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2012-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120048377-A1 PHOTOSENSITIVE OPTOELECTRONIC DEVICES COMPRISING POLYCYCLIC AROMATIC COMPOUNDS TYR, PAH, DDT CACNA2D1 1837/4885CACNB2 2464/4885CACNA1C 1891/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.