SCHEMBL4462846

SCHEMBL4462846

CN(C)C(N)=C(N(C)C)N(C)C

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.30
DPP4 P27487 1/20 0.30
ADRA1A P35348 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL614351 0.69 LMNA (0.31) LMNADPP4ADRA1A
SCHEMBL8050782 0.69
SCHEMBL309032 0.69 TAS2R38 (0.39) LMNA
SCHEMBL4051119 0.67 LMNA (0.35) LMNADPP4ADRA1A
SCHEMBL16935761 0.65
SCHEMBL24324774 0.65
SCHEMBL27752228 0.61
SCHEMBL13458239 0.60 LMNA (0.36) LMNADPP4ADRA1A
SCHEMBL11609722 0.60 KMT2A (0.43) LMNA
SCHEMBL33703 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1976817-A2 PREPARATION OF ALKYL KETENE DIMERS Hercules Incorporated (US) 2008-10-08 EP claimed
WO-2007079444-A2 PREPARATION OF ALKYL KETENE DIMERS HERCULES INCORPORATED (US) 2007-07-12 WO claimed
EP-1524289-B1 POLYMERIZABLE COMPOSITION, OPTICAL MATERIAL COMPRISING THE COMPOSITION AND METHOD FOR PRODUCING THE MATERIAL MITSUBISHI GAS CHEMICAL CO (JP) 2009-09-16 EP disclosed
EP-1976817-A2 PREPARATION OF ALKYL KETENE DIMERS Hercules Incorporated (US) 2008-10-08 EP disclosed
WO-2007079444-A2 PREPARATION OF ALKYL KETENE DIMERS HERCULES INCORPORATED (US) 2007-07-12 WO disclosed
US-20070149639-A1 Polymerizable composition, optical material comprising the composition and method for producing the material HORIKOSHI HIROSHI 2007-06-28 US disclosed
EP-1524289-A1 POLYMERIZABLE COMPOSITION, OPTICAL MATERIAL COMPRISING THE COMPOSITION AND METHOD FOR PRODUCING THE MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2005-04-20 EP disclosed
US-20040254258-A1 Polymerizable composition, optical material comprising the composition and method for producing the material MITSUBISHI GAS CHEMICAL CO., LTD. (JP) 2004-12-16 US disclosed