SCHEMBL614351

SCHEMBL614351

CC(N)=C(N(C)C)N(C)C

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.31
ALOX15 P16050 1/20 0.31
BLM P54132 1/20 0.31
PMP22 Q01453 1/20 0.31
DPP4 P27487 1/20 0.30
ADRA1A P35348 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27752228 0.70
SCHEMBL2766558 0.69
SCHEMBL370004 0.69
SCHEMBL4462846 0.69 LMNA (0.30) LMNADPP4ADRA1A
SCHEMBL18869864 0.69
SCHEMBL309032 0.69 TAS2R38 (0.39) LMNAALOX15PMP22
SCHEMBL10665755 0.67 TAS2R38 (0.31)
SCHEMBL16935761 0.65
SCHEMBL18570151 0.64 KDM4E (0.32) LMNAALOX15
SCHEMBL7194403 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8728225-B2 Composition containing quaternary amino-functional organosilicon compounds and production and use thereof EVONIK DEGUSSA GMBH (DE) 2014-05-20 US claimed
EP-0525881-B1 Catalyzed hydrocarbyllithium process FMC CORP (US) 1998-06-24 EP claimed
EP-0525880-B1 Catalytic alkylation process FMC CORP (US) 1998-05-06 EP claimed
US-5340507-A Alkylating alkali metal with alkyl halide in hydrocarbon solvent in presence of specified catalyst FMC CORPORATION (US) 1994-08-23 US claimed
US-5332853-A Alkylating tetrachlorosilane or an alkylchlorosilane with an alkyllithium using ether, metal alkoxide, amine, or metal amide as catalyst FMC CORPORATION (US) 1994-07-26 US claimed
US-5211888-A Alkylation FMC CORPORATION (US) 1993-05-18 US claimed
EP-0525880-A1 Catalytic alkylation process FMC CORPORATION (US) 1993-02-03 EP claimed
EP-0525881-A1 Catalyzed hydrocarbyllithium process FMC CORPORATION (US) 1993-02-03 EP claimed
WO-2021261241-A1 HYDROGENATED COPOLYMER, RESIN COMPOSITION, MOLDED BODY AND ADHESIVE FILM 旭化成株式会社 2021-12-30 WO disclosed
US-20210301070-A1 ALLOPHANATE GROUP-CONTAINING POLYISOCYANATE COMPOSITION, POLYURETHANE RESIN-FORMING COMPOSITION, SEAL MATERIAL, MEMBRANE MODULE TOSOH CORPORATION (JP) 2021-09-30 US disclosed
EP-3828216-A1 ALLOPHANATE GROUP-CONTAINING POLYISOCYANATE COMPOSITION, POLYURETHANE RESIN-FORMING COMPOSITION, SEAL MATERIAL, MEMBRANE MODULE Tosoh Corporation (JP) 2021-06-02 EP disclosed
CN-112513126-A Allophanate group-containing polyisocyanate composition, urethane resin-forming composition, sealing material, and film assembly 东曹株式会社 2021-03-16 CN disclosed
WO-2020235521-A1 HYDROGENATED COPOLYMER, ADHESIVE FILM, RESIN COMPOSITION, AND MOLDED ARTICLE 旭化成株式会社 (JP) 2020-11-26 WO disclosed
US-10829442-B2 Process for the preparation of carbamates TAMINCO BVBA (BE) 2020-11-10 US disclosed
EP-0279325-B1 (+)-1R-TRANS-2,2-DIMETHYL-3-(2,2-DICHLOROVINYL)CYCLOPROPANECARBOXYLIC ACID 2,3,5,6-TETRAFLUOROBENZYL ESTER BAYER AG (DE) 1990-05-16 EP disclosed
US-4820735-A INSECTICIDES, MITICIDES BAYER AKTIENGESELLSCHAFT (DE) 1989-04-11 US disclosed
EP-0200943-B1 VINYLCYCLOPROPANECARBOXYLIC-ACID ESTERS BAYER AG (DE) 1988-12-07 EP disclosed
EP-0279325-A2 (+)-1R-trans-2,2-dimethyl-3-(2,2-dichlorovinyl)cyclopropanecarboxylic acid 2,3,5,6-tetrafluorobenzyl ester BAYER AG (DE) 1988-08-24 EP disclosed
US-4699922-A PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1987-10-13 US disclosed
EP-0200943-A1 Vinylcyclopropanecarboxylic-acid esters BAYER AG (DE) 1986-11-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10829442-B2 Process for the preparation of carbamates CPS1, GLUL, CBR3 LMNA 3163/4885ALOX15 2217/4885BLM 3286/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.