Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6421876 | 0.97 | LMNA (0.64) | LMNASLC6A4SLC6A2SLC6A3HSD17B10 | |
| SCHEMBL2905656 | 0.89 | LMNA (0.56) | LMNASLC6A4SLC6A2SLC6A3HSD17B10 | |
| SCHEMBL11251072 | 0.88 | SLC6A4 (0.55) | LMNASLC6A4SLC6A2SLC6A3HSD17B10 | |
| SCHEMBL8234489 | 0.86 | LMNA (0.51) | LMNASLC6A4SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL4039568 | 0.84 | SLC6A4 (0.51) | LMNASLC6A4SLC6A2SLC6A3HSD17B10 | |
| SCHEMBL9277493 | 0.83 | LMNA (0.71) | LMNAHSD17B10NPSR1ALDH1A1PKM | |
| SCHEMBL4143905 | 0.83 | LMNA (0.71) | LMNASLC6A2SLC6A3HSD17B10NPSR1 | |
| SCHEMBL9309772 | 0.83 | SLC6A4 (0.50) | LMNASLC6A4SLC6A2SLC6A3HSD17B10 | |
| Hydrochloric Acid SCHEMBL9096753 | 0.82 | LMNA (0.69) | LMNASLC6A2SLC6A3HSD17B10NPSR1 | |
| SCHEMBL9164261 | 0.81 | TACR1 (0.53) | LMNASLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544687-B2 | Substituted α-piperazinyl phenylpropionic acid derivatives as hPPAR α and/or hPPAR γ agonists | BEIJING MOLECULE SCIENCE AND TECHNOLOGY CO., LTD (CN) | 2009-06-09 | — | — | US | disclosed |
| US-7544687-B2 | Substituted α-piperazinyl phenylpropionic acid derivatives as hPPAR α and/or hPPAR γ agonists | BEIJING MOLECULE SCIENCE AND TECHNOLOGY CO., LTD (CN) | 2009-06-09 | — | — | US | disclosed |
| US-20070259883-A1 | Substitued A-Piperazingly Phenylpropionic Acid Derivatives As Hppar Alpha And/Or Hppar Gamma Agonists | BEIJING MOLECULE SCIENCE AND TECHNOLOGY CO., LTD. (CN) | 2007-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259883-A1 | Substitued A-Piperazingly Phenylpropionic Acid Derivatives As Hppar Alpha And/Or Hppar Gamma Agonists | GPR119, PPARG, PPARA | LMNA 1955/4885SLC6A4 1920/4885SLC6A2 2638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.