SCHEMBL4463285

SCHEMBL4463285

CC(=O)N(Cc1ccco1)C(C)=O

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.56
ALDH1A1 P00352 2/20 0.53
MAPK1 P28482 2/20 0.52
NPSR1 Q6W5P4 2/20 0.52
TSHR P16473 1/20 0.52
RIPK1 Q13546 1/20 0.51
POLB P06746 1/20 0.48
TP53 P04637 1/20 0.47
MAPT P10636 3/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
HSD11B1 P28845 1/20 0.47
GFER P55789 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21393181 0.86 MAPK1 (0.66) ALOX5ALDH1A1MAPK1NPSR1TSHR
SCHEMBL11967793 0.83 RIPK1 (0.62) ALOX5ALDH1A1MAPK1NPSR1TSHR
SCHEMBL28226220 0.80 MAPK1 (0.59) ALOX5ALDH1A1MAPK1NPSR1TSHR
SCHEMBL5130457 0.78 RIPK1 (0.60) ALOX5ALDH1A1MAPK1NPSR1RIPK1
SCHEMBL13197673 0.78 MAPK1 (0.64) ALOX5ALDH1A1MAPK1NPSR1TSHR
SCHEMBL9345778 0.78 ALOX5 (0.49) ALOX5ALDH1A1MAPK1NPSR1TSHR
SCHEMBL16316820 0.76 MAPK1 (0.59) ALOX5ALDH1A1MAPK1NPSR1TSHR
SCHEMBL19002782 0.76 HTT (0.51) ALOX5ALDH1A1MAPK1NPSR1TSHR
SCHEMBL28116359 0.76 RIPK1 (0.62) ALOX5ALDH1A1MAPK1NPSR1TSHR
SCHEMBL20982038 0.75 ALOX5 (0.50) ALOX5ALDH1A1MAPK1NPSR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1489109-B1 Living and quasiliving cationic telechelic polymers quenched by N-substituted pyrrole and methods for their preparation CHEVRON ORONITE CO (US) 2015-08-19 EP disclosed
US-7576161-B2 Process for preparing terminally functionalized living and quasiliving cationic telechelic polymers CHEVRON ORONITE COMPANY LLC (US) 2009-08-18 US disclosed
US-20050282972-A1 Process for preparing terminally functionalized living and quasiliving cationic telechelic polymers STOKES CASEY D 2005-12-22 US disclosed
US-6969744-B2 Living and quasiliving cationic telechelic polymers quenched by N-substituted pyrrole and methods for their preparation UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2005-11-29 US disclosed
EP-1489109-A2 Living and quasiliving cationic telechelic polymers quenched by N-substituted pyrrole and methods for their preparation Chevron Oronite Company LLC (US) 2004-12-22 EP disclosed