Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 7/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | TMPRSS4 | Q9NRS4 | 6/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3417238 | 0.85 | MEN1 (0.46) | P2RX1HSP90AA1HSP90AB1CFTRCA12 | |
| SCHEMBL4116150 | 0.84 | MEN1 (0.45) | P2RX1HSP90AA1HSP90AB1CFTRCA12 | |
| Potassium Ion SCHEMBL4798604 | 0.82 | HSP90AA1 (0.40) | P2RX1HSP90AA1HSP90AB1TMPRSS4P2RX4 | |
| SCHEMBL3417227 | 0.70 | CNR1 (0.46) | P2RX1TMPRSS4P2RX4P2RX7PIK3CA | |
| SCHEMBL26181060 | 0.70 | RORC (0.45) | P2RX1HSP90AA1HSP90AB1TMPRSS4CFTR | |
| SCHEMBL3417230 | 0.69 | TMPRSS4 (0.44) | P2RX1TMPRSS4P2RX4P2RX7CFTR | |
| SCHEMBL25963027 | 0.69 | CA12 (0.64) | HSP90AA1CA12CA1CA2CA7 | |
| SCHEMBL5512932 | 0.67 | ALDH1A1 (0.48) | CRHBPCRHR2NPSR1 | |
| SCHEMBL21367459 | 0.67 | CFTR (0.49) | P2RX1HSP90AA1HSP90AB1TMPRSS4P2RX4 | |
| SCHEMBL13280707 | 0.67 | CFTR (0.64) | P2RX1TMPRSS4P2RX4P2RX7CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009045083-A2 | COMBINATION THERAPY FOR NEUROPROTECTION | S.H. PHARMA., LTD (KR) | 2009-04-09 | — | — | WO | disclosed |