Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 5/20 | 0.46 |
| ▸ | CTSS | P25774 | 5/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 7/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.38 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4458412 | 0.92 | CTSL (0.44) | CTSLCTSSHCRTR1ELANEHTT | |
| SCHEMBL4458411 | 0.92 | CTSL (0.44) | CTSLCTSSHCRTR1ELANEHTT | |
| SCHEMBL4469682 | 0.91 | CTSL (0.43) | CTSLCTSSHCRTR1ELANEHTT | |
| SCHEMBL13606505 | 0.91 | CTSL (0.43) | CTSLCTSSHCRTR1ELANEHTT | |
| SCHEMBL4469679 | 0.91 | CTSL (0.43) | CTSLCTSSHCRTR1ELANEHTT | |
| SCHEMBL4461483 | 0.84 | ELANE (0.53) | CTSSELANE | |
| SCHEMBL4456597 | 0.84 | ELANE (0.53) | CTSSELANE | |
| SCHEMBL4558354 | 0.81 | CTSS (0.45) | CTSLCTSSHCRTR1S1PR1S1PR3 | |
| SCHEMBL4457207 | 0.80 | ELANE (0.52) | CTSSELANE | |
| SCHEMBL4457090 | 0.77 | CTSS (0.43) | CTSLCTSSHCRTR1KITDDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | claimed |
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |