Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 6/20 | 0.43 |
| ▸ | CTSL | P07711 | 5/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4558354 | 0.84 | CTSS (0.45) | CTSSCTSLHCRTR1PTGDR2DAGLA | |
| SCHEMBL4463467 | 0.77 | CTSL (0.46) | CTSSCTSLHCRTR1DAGLAKIT | |
| SCHEMBL4457088 | 0.77 | CTSS (0.39) | CTSSCTSLHCRTR1PTGDR2DAGLA | |
| SCHEMBL13606505 | 0.75 | CTSL (0.43) | CTSSCTSLHCRTR1PTGDR2KIT | |
| SCHEMBL4458412 | 0.74 | CTSL (0.44) | CTSSCTSLHCRTR1PTGDR2DAGLA | |
| SCHEMBL4458411 | 0.74 | CTSL (0.44) | CTSSCTSLHCRTR1PTGDR2DAGLA | |
| SCHEMBL4469679 | 0.73 | CTSL (0.43) | CTSSCTSLHCRTR1PTGDR2DAGLA | |
| SCHEMBL4469682 | 0.73 | CTSL (0.43) | CTSSCTSLHCRTR1PTGDR2DAGLA | |
| SCHEMBL4453282 | 0.68 | NPC1 (0.43) | CTSSMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL4457207 | 0.67 | ELANE (0.52) | CTSSMEN1KMT2AALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |