Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | HMGCR | P04035 | 4/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8163207 | 0.77 | ATM (0.38) | ALDH1A1MAPTKMT2AATMNPC1 | |
| SCHEMBL4468492 | 0.74 | ATM (0.40) | ALDH1A1MAPTKMT2ATHRBATM | |
| SCHEMBL85988 | 0.73 | ATM (0.42) | ALDH1A1MAPTKMT2ATHRBATM | |
| SCHEMBL4457743 | 0.71 | KMT2A (0.38) | ALDH1A1MAPTKMT2ATHRBATM | |
| SCHEMBL85970 | 0.66 | ATM (0.49) | ALDH1A1MAPTKMT2AATMNPC1 | |
| SCHEMBL8675243 | 0.66 | ATM (0.39) | ALDH1A1MAPTKMT2AATMNPC1 | |
| SCHEMBL14307454 | 0.65 | ATM (0.44) | ALDH1A1MAPTKMT2AATMNPC1 | |
| SCHEMBL22930710 | 0.65 | ATM (0.44) | ALDH1A1MAPTKMT2AATMNPC1 | |
| SCHEMBL8410304 | 0.65 | ATM (0.44) | ALDH1A1MAPTKMT2AATMNPC1 | |
| SCHEMBL86001 | 0.65 | ATM (0.41) | ALDH1A1MAPTKMT2AATMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7045647-B2 | Blends of quinone alkide and nitroxyl compounds and polymerization inhibitors | UNIROYAL CHEMICAL COMPANY, INC. (US) | 2006-05-16 | — | — | US | claimed |
| EP-1379584-B1 | FLAME RETARDANT COMPOSITIONS | CIBA SC HOLDING AG (CH) | 2005-08-24 | — | — | EP | claimed |
| EP-0737659-B1 | 7-Substituted quinone methides as inhibitors for unsaturated monomers | CIBA SC HOLDING AG (CH) | 2000-07-05 | — | — | EP | claimed |
| US-7473795-B2 | Blends of quinone alkide and nitroxyl compounds as polymerization inhibitors | UNIROYAL CHEMICAL COMPANY, INC. (US) | 2009-01-06 | — | — | US | disclosed |