Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16104561 | 0.83 | ATM (0.38) | ATMKMT2ANPC1GPR35ALDH1A1 | |
| SCHEMBL16104563 | 0.80 | ATM (0.37) | ATMKMT2ANPC1GPR35ALDH1A1 | |
| SCHEMBL85970 | 0.79 | ATM (0.49) | ATMKMT2ANPC1GPR35ALDH1A1 | |
| SCHEMBL16104560 | 0.74 | ATM (0.42) | ATMKMT2ANPC1GPR35ALDH1A1 | |
| SCHEMBL4468463 | 0.73 | ATM (0.41) | ATMKMT2ANPC1GPR35ALDH1A1 | |
| SCHEMBL4463546 | 0.73 | ALDH1A1 (0.41) | ATMKMT2ANPC1GPR35ALDH1A1 | |
| SCHEMBL4457743 | 0.73 | KMT2A (0.38) | ATMKMT2ANPC1GPR35ALDH1A1 | |
| SCHEMBL4456520 | 0.71 | ATM (0.40) | ATMKMT2ANPC1GPR35ALDH1A1 | |
| SCHEMBL8676354 | 0.71 | ATM (0.45) | ATMKMT2ANPC1GPR35ALDH1A1 | |
| SCHEMBL29165174 | 0.71 | KMT2A (0.46) | ATMKMT2ANPC1GPR35ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2243764-B1 | Method for producing substituted 1.4 chinonmethides | EVONIK DEGUSSA GMBH (DE) | 2017-06-07 | — | — | EP | disclosed |
| US-9670116-B2 | Process and composition for inhibiting the polymerization of cyclopentadiene compounds | EVONIK DEGUSSA GMBH (DE) | 2017-06-06 | — | — | US | disclosed |
| US-9670116-B2 | Process and composition for inhibiting the polymerization of cyclopentadiene compounds | EVONIK DEGUSSA GMBH (DE) | 2017-06-06 | — | — | US | disclosed |
| US-9493382-B2 | Process and composition for inhibiting the polymerization of cyclopentadiene compounds | EVONIK DEGUSSA GMBH (DE) | 2016-11-15 | — | — | US | disclosed |
| US-9493382-B2 | Process and composition for inhibiting the polymerization of cyclopentadiene compounds | EVONIK DEGUSSA GMBH (DE) | 2016-11-15 | — | — | US | disclosed |
| EP-2781496-B1 | Method and composition for inhibiting the polymerisation of cyclopentadiene compounds | EVONIK DEGUSSA GMBH (DE) | 2016-09-21 | — | — | EP | disclosed |
| US-20160237008-A1 | PROCESS AND COMPOSITION FOR INHIBITING THE POLYMERIZATION OF CYCLOPENTADIENE COMPOUNDS | EVONIK DEGUSSA GMBH (DE) | 2016-08-18 | — | — | US | disclosed |
| US-20160237346-A1 | PROCESS AND COMPOSITION FOR INHIBITING THE POLYMERIZATION OF CYCLOPENTADIENE COMPOUNDS | EVONIK DEGUSSA GMBH (DE) | 2016-08-18 | — | — | US | disclosed |
| US-20160237008-A1 | PROCESS AND COMPOSITION FOR INHIBITING THE POLYMERIZATION OF CYCLOPENTADIENE COMPOUNDS | EVONIK DEGUSSA GMBH (DE) | 2016-08-18 | — | — | US | disclosed |
| US-20160237346-A1 | PROCESS AND COMPOSITION FOR INHIBITING THE POLYMERIZATION OF CYCLOPENTADIENE COMPOUNDS | EVONIK DEGUSSA GMBH (DE) | 2016-08-18 | — | — | US | disclosed |
| US-20120101295-A1 | PROCESS FOR STABILIZING OLEFINICALLY UNSATURATED MONOMERS | EVONIK DEGUSSA GMBH (DE) | 2012-04-26 | — | — | US | disclosed |
| US-8128804-B2 | Process for stabilizing olefinically unsaturated monomers | EVONIK DEGUSSA GMBH (DE) | 2012-03-06 | — | — | US | disclosed |
| US-8128804-B2 | Process for stabilizing olefinically unsaturated monomers | EVONIK DEGUSSA GMBH (DE) | 2012-03-06 | — | — | US | disclosed |
| EP-2243764-A1 | Method for producing substituted 1,4 chinonmethides | Evonik Degussa GmbH (DE) | 2010-10-27 | — | — | EP | disclosed |
| US-20100267992-A1 | PROCESS FOR PREPARING SUBSTITUTED 1,4-QUINONE METHIDES | EVONIK DEGUSSA GMBH (DE) | 2010-10-21 | — | — | US | disclosed |
| US-20090114878-A1 | PROCESS FOR STABILIZING OLEFINICALLY UNSATURATED MONOMERS | EVONIK DEGUSSA GMBH (DE) | 2009-05-07 | — | — | US | disclosed |
| US-20090114878-A1 | PROCESS FOR STABILIZING OLEFINICALLY UNSATURATED MONOMERS | EVONIK DEGUSSA GMBH (DE) | 2009-05-07 | — | — | US | disclosed |
| EP-0626377-B1 | Method for producing benzylidene derivatives | SHIONOGI & CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5463052-A | Nonsteroidal antiinflammatory agents | SHIONOGI & CO., LTD. (JP) | 1995-10-31 | — | — | US | disclosed |
| EP-0626377-A1 | Method for producing benzylidene derivatives | SHIONOGI & CO., LTD. (JP) | 1994-11-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101295-A1 | PROCESS FOR STABILIZING OLEFINICALLY UNSATURATED MONOMERS | SQOR, ALOX12, ALOX15B | ATM 4714/4885KMT2A 2863/4885NPC1 3870/4885 |
| US-20100267992-A1 | PROCESS FOR PREPARING SUBSTITUTED 1,4-QUINONE METHIDES | NQO1, SQOR, SDHA | ATM 3339/4885KMT2A 382/4885NPC1 4830/4885 |
| US-20160237008-A1 | PROCESS AND COMPOSITION FOR INHIBITING THE POLYMERIZATION OF CYCLOPENTADIENE COMPOUNDS | CYC1, SQOR, UQCRB | ATM 2053/4885KMT2A 4303/4885NPC1 4103/4885 |
| US-20160237346-A1 | PROCESS AND COMPOSITION FOR INHIBITING THE POLYMERIZATION OF CYCLOPENTADIENE COMPOUNDS | CYC1, SQOR, UQCRB | ATM 2053/4885KMT2A 4303/4885NPC1 4103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.