Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | BTN3A1 | O00481 | 3/20 | 0.37 |
| ▸ | MVD | P53602 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL444062 | 0.84 | — | — | |
| Triphosphate SCHEMBL18714 | 0.84 | FDPS (0.69) | FDPSBLMTDP1BTN3A1MVD | |
| Triphosphate SCHEMBL15555988 | 0.84 | FDPS (0.69) | FDPSBLMTDP1BTN3A1MVD | |
| Triphosphate SCHEMBL11149492 | 0.81 | FDPS (0.64) | FDPSBLMTDP1BTN3A1MVD | |
| Triphosphate SCHEMBL21246913 | 0.81 | FDPS (0.64) | FDPSBLMTDP1BTN3A1MVD | |
| Triphosphate SCHEMBL25284822 | 0.81 | FDPS (0.64) | FDPSBLMTDP1BTN3A1MVD | |
| Triphosphate SCHEMBL3253186 | 0.81 | FDPS (0.64) | FDPSBLMTDP1BTN3A1MVD | |
| Triphosphate SCHEMBL22717549 | 0.81 | FDPS (0.64) | FDPSBLMTDP1BTN3A1MVD | |
| Triphosphate SCHEMBL9632051 | 0.81 | FDPS (0.64) | FDPSBLMTDP1BTN3A1MVD | |
| Triphosphate SCHEMBL36119 | 0.81 | FDPS (0.64) | FDPSBLMTDP1BTN3A1MVD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8354524-B2 | Synthesis of selenium-derivatized nucleosides, nucleotides, phosphoramidites, triphosphates and nucleic acids | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2013-01-15 | — | — | US | claimed |
| US-20120065387-A1 | SYNTHESIS OF SELENIUM-DERIVATIZED NUCLEOSIDES, NUCLEOTIDES, PHOSPHORAMIDITES, TRIPHOSPHATES AND NUCLEIC ACIDS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2012-03-15 | — | — | US | claimed |
| US-7982030-B2 | Synthesis of selenium-derivatized nucleosides, nucleotides, phosphoramidites, triphosphates and nucleic acids | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2011-07-19 | — | — | US | claimed |
| US-20100137573-A1 | SYNTHESIS OF SELENIUM-DERIVATIZED NUCLEOSIDES, NUCLEOTIDES, PHOSPHORAMIDITES, TRIPHOSPHATES AND NUCLEIC ACIDS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2010-06-03 | — | — | US | claimed |
| US-7592446-B2 | Useful in structural determinations, particularly by X-ray crystallographic techniques; useful as food supplements | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2009-09-22 | — | — | US | claimed |
| WO-2008080060-A2 | 4-SE-THYMIDINE DERIVATIVES, 4-SE-URIDINE DERIVATIVES, DI (2-CYANOETHYL) DISELENIDE, AND METHODS | GEORGIA STATE UNIVERSITY (US) | 2008-07-03 | — | — | WO | claimed |
| US-20030055016-A1 | Synthesis of selenium-derivatized nucleosides, nucleotides, phosphoramidites, triphosphates and nucleic acids | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-03-20 | — | — | US | claimed |
| WO-2002077002-A2 | SYNTHESIS OF SELENIUM-DERIVATIZED NUCLEOSIDES, NUCLEOTIDES, PHOSPHORAMIDITES, TRIPHOSPHATES AND NUCLEIC ACIDS | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2002-10-03 | — | — | WO | claimed |
| US-8354524-B2 | Synthesis of selenium-derivatized nucleosides, nucleotides, phosphoramidites, triphosphates and nucleic acids | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2013-01-15 | — | — | US | disclosed |
| US-20120065387-A1 | SYNTHESIS OF SELENIUM-DERIVATIZED NUCLEOSIDES, NUCLEOTIDES, PHOSPHORAMIDITES, TRIPHOSPHATES AND NUCLEIC ACIDS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2012-03-15 | — | — | US | disclosed |
| US-7982030-B2 | Synthesis of selenium-derivatized nucleosides, nucleotides, phosphoramidites, triphosphates and nucleic acids | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2011-07-19 | — | — | US | disclosed |
| US-20100137573-A1 | SYNTHESIS OF SELENIUM-DERIVATIZED NUCLEOSIDES, NUCLEOTIDES, PHOSPHORAMIDITES, TRIPHOSPHATES AND NUCLEIC ACIDS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2010-06-03 | — | — | US | disclosed |
| US-7592446-B2 | Useful in structural determinations, particularly by X-ray crystallographic techniques; useful as food supplements | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2009-09-22 | — | — | US | disclosed |
| WO-2008080060-A3 | 4-SE-THYMIDINE DERIVATIVES, 4-SE-URIDINE DERIVATIVES, DI (2-CYANOETHYL) DISELENIDE, AND METHODS | UNIV GEORGIA STATE (US) | 2008-11-27 | — | — | WO | disclosed |
| WO-2008080060-A2 | 4-SE-THYMIDINE DERIVATIVES, 4-SE-URIDINE DERIVATIVES, DI (2-CYANOETHYL) DISELENIDE, AND METHODS | GEORGIA STATE UNIVERSITY (US) | 2008-07-03 | — | — | WO | disclosed |
| WO-2008080060-A2 | 4-SE-THYMIDINE DERIVATIVES, 4-SE-URIDINE DERIVATIVES, DI (2-CYANOETHYL) DISELENIDE, AND METHODS | GEORGIA STATE UNIVERSITY (US) | 2008-07-03 | — | — | WO | disclosed |
| US-20030055016-A1 | Synthesis of selenium-derivatized nucleosides, nucleotides, phosphoramidites, triphosphates and nucleic acids | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-03-20 | — | — | US | disclosed |
| WO-2002077002-A2 | SYNTHESIS OF SELENIUM-DERIVATIZED NUCLEOSIDES, NUCLEOTIDES, PHOSPHORAMIDITES, TRIPHOSPHATES AND NUCLEIC ACIDS | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2002-10-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055016-A1 | Synthesis of selenium-derivatized nucleosides, nucleotides, phosphoramidites, triphosphates and nucleic acids | SELENOI, NT5C3B, RNGTT | FDPS 306/4885BLM 632/4885TDP1 424/4885 |
| US-20100137573-A1 | SYNTHESIS OF SELENIUM-DERIVATIZED NUCLEOSIDES, NUCLEOTIDES, PHOSPHORAMIDITES, TRIPHOSPHATES AND NUCLEIC ACIDS | SELENOI, RNGTT, NT5C3B | FDPS 315/4885BLM 621/4885TDP1 384/4885 |
| US-20120065387-A1 | SYNTHESIS OF SELENIUM-DERIVATIZED NUCLEOSIDES, NUCLEOTIDES, PHOSPHORAMIDITES, TRIPHOSPHATES AND NUCLEIC ACIDS | SELENOI, RNGTT, NT5C3B | FDPS 315/4885BLM 621/4885TDP1 384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.